1048988-06-2Relevant academic research and scientific papers
Oxidative coupling of indoles using thallium(III) trifluoroacetate
Keller, Paul A.,Yepuri, Nageshwar R.,Kelso, Michael J.,Mariani, Michael,Skelton, Brian W.,White, Allan H.
, p. 7787 - 7795 (2008/12/21)
The oxidative coupling of polysubstituted electron-rich indoles mediated by thallium trifluoroacetate was found to be a facile, clean, and high yielding reaction. Indolic coupling sites were determined by the nature of the substituents present, with dimerisation at the indole 2-position being the dominant outcome. Indoles bearing two potential reaction sites with similar reactivity were additionally found to undergo heterocoupling.
