1048990-90-4

Upstream product

• 1048992-96-6 methyl 5-chloro-2-phenylbenzofuran-7-carboxylate 
• 122996-96-7 (5-chloro-2-phenyl-benzofuran-7-yl)methanol 
• 1048993-59-4 (5-chloro-2-phenyl-benzofuran-7-yl)methyl methanesulfonate 
• 4068-78-4 methyl 5-chloro-2-hydroxybenzoate 
• 4068-71-7 methyl 3-bromo-5-chloro-2-hydroxybenzoate 
• 1048993-21-0 ethyl 1-[(5-chloro-2-phenyl-benzofuran-7-yl)methyl]-5-methyl-1H-pyrazole-3-carboxylate 

Downstream Products

• 1048993-75-4 2-(trimethylsilyl)ethyl {1-[(5-chloro-2-phenyl-benzofuran-7-yl)methyl]-5-methyl-1H-pyrazol-3-yl}carbamate 
• 1048991-83-8 1-[(5-chloro-2-phenyl-benzofuran-7-yl)methyl]-5-methyl-N-(1-methylethyl)-1H-pyrazole-3-carboxamide 
• 1048993-93-6 1-{(5-chloro-2-phenyl-benzofuran-7-yl)methyl}-N-{4-(hydroxymethyl)phenyl}-5-methyl-1H-pyrazole-3-carboxamide 
• 1048994-07-5 methyl 6-(((1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-1H-pyrazol-3-yl)carbonyl)amino)-3-pyridinecarboxylate 
• 1048991-63-4 1-((5-chloro-2-phenyl-benzofuran-7-yl)methyl)-5-methyl-N-4-morpholinyl-1H-pyrazole-3-carboxamide 
• 1048993-80-1 1-[(5-chloro-2-phenyl-benzofuran-7-yl)methyl]-5-methyl-1H-pyrazol-3-amine 

Relevant academic research and scientific papers

Discovery of a novel series of nonacidic benzofuran EP1 receptor antagonists

We describe the discovery and optimization of a novel series of benzofuran EP1 antagonists, leading to the identification of 26d, a novel nonacidic EP1 antagonist which demonstrated efficacy in preclinical models of chronic inflammat

BENZOFURAN COMPOUNDS

A compound of formula (I), wherein R1, R2, and R3 are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in