4068-71-7Relevant academic research and scientific papers
BENZO-FUSED HETEROCYCLIC DERIVATIVES USEFUL AS AGONISTS OF GPR120
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Paragraph 0608, (2014/09/30)
The present invention is directed to benzo-fused heterocyclic derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by GPR120. More particularly, the compounds of the present invention are agonists of GPR120, useful in the treatment of, such as for example, Type II diabetes mellitus.
Discovery of a novel series of nonacidic benzofuran EP1 receptor antagonists
Allan, Amanda C.,Billinton, Andy,Brown, Susan H.,Chowdhury, Anita,Eatherton, Andrew J.,Fieldhouse, Charlotte,Giblin, Gerard M.P.,Goldsmith, Paul,Hall, Adrian,Hurst, David N.,Naylor, Alan,Rawlings, D. Anthony,Sime, Mairi,Scoccitti, Tiziana,Theobald, Pamela J.
scheme or table, p. 4343 - 4348 (2011/08/06)
We describe the discovery and optimization of a novel series of benzofuran EP1 antagonists, leading to the identification of 26d, a novel nonacidic EP1 antagonist which demonstrated efficacy in preclinical models of chronic inflammat
BENZOFURAN COMPOUNDS
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Page/Page column 37, (2008/12/08)
A compound of formula (I), wherein R1, R2, and R3 are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in
BENZOFURAN COMPOUNDS AS EP1 RECEPTOR ANTAGONISTS
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Page/Page column 35-36, (2008/06/13)
Compounds of formula (I) or a pharmaceutically acceptable derivative thereof, wherein R1,R2a, R2b, R2c, and R3 are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.
