104920-79-8

Basic information

• Product Name: Benzeneacetic acid, 4-fluoro-.alpha.-forMyl-, ethyl ester
• Synonyms: Benzeneacetic acid, 4-fluoro-.alpha.-forMyl-, ethyl ester
• CAS NO: 104920-79-8
• Molecular Formula: C₁₁H₁₁FO₃
• Molecular Weight: 210.2016432
• Mol File: 104920-79-8.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzeneacetic acid, 4-fluoro-.alpha.-forMyl-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, 4-fluoro-.alpha.-forMyl-, ethyl ester(104920-79-8)
• EPA Substance Registry System: Benzeneacetic acid, 4-fluoro-.alpha.-forMyl-, ethyl ester(104920-79-8)

Safety Data

• Hazardous Substances Data: 104920-79-8(Hazardous Substances Data)

Usage

General Description

Benzeneacetic acid, 4-fluoro-.alpha.-forMyl-, ethyl ester is a chemical compound with the molecular formula C11H11FO2. It is an ethyl ester derivative of 4-fluoro-α-methyl benzeneacetic acid. Benzeneacetic acid, 4-fluoro-.alpha.-forMyl-, ethyl ester is often used in the field of organic chemistry and pharmaceutical research as a building block for the synthesis of various pharmaceutical drugs and other organic compounds. It is also known for its potential therapeutic applications, particularly in the development of analgesic and anti-inflammatory medications. Additionally, it is commonly used as a reagent in chemical reactions and organic synthesis processes due to its unique chemical properties.

Upstream product

• 109-94-4 formic acid ethyl ester 
• 587-88-2 ethyl 2-(4-fluorophenyl)acetate 

Downstream Products

• 104920-80-1 7-amino-3-(4-fluorophenyl)-2-hydroxy-1,8-naphthyridine 
• 104920-88-9 8-amino-4-(4-fluorophenyl)tetrazolo<1,5-a><1,8>naphthyridine 
• 104920-91-4 8-hydroxy-4-(4-fluorophenyl)tetrazolo<1,5-a><1,8>naphthyridine 
• 104949-89-5 7-acetamido-2-chloro-3-(4-fluorophenyl)-1,8-naphthyridine 
• 104949-87-3 7-acetamido-3-(4-fluorophenyl)-2-hydroxy-1,8-naphthyridine 
• 104920-85-6 8-acetamido-4-(4-fluorophenyl)tetrazolo<1,5-a><1,8>naphthyridine 

Relevant articles and documents

Study on the synthesis and biological activities of α-substituted arylacetates derivatives

Anisodamine was isolated from the medicinal herb, it was used in the treatment of gastrointestinal smooth muscle spasm, infective toxic shock and organophosphorus intoxication. But there is no report about anisodamine with α-glucosidase inhibitory activity. In order to find novel α-glucosidase inhibitors, a series of α-substituted arylacetates derivatives have been synthesized based on the active unit of anisodamine. In α-glucosidase assay, compound 9 in Schiff base form and compound 22 in ester form show strong inhibition against α-glucosidase with IC50value of 46.81?μM and 83.76?μM, respectively. Compounds 9 and 22 exhibit comparable good antidiabetic activities as commercial drug Glimepiride. In addition, Schiff bases of α-substituted arylacetates show antitumor activities against human cancer cell lines, where compound 9 with thiourea moiety performs the best antitumor activity. We anticipate that our research will provide potential candidate scaffolds for antidiabetic drug design.

Lewis base catalyzed asymmetric hydrosilylation of α-substituted β-enamino esters: Facile access to enantioenriched β2-amino esters via dynamic kinetic resolution

A chiral Lewis base organocatalyzed asymmetric hydrosilylation of α-substituted β-enamino esters is presented. The reactions proceeded through dynamic kinetic resolution to afford various enantioenriched β2-amino esters with high yields (up to

Synthesis of new 6H-indolo[2,3-b] [1,8]naphthyridines and their specific inhibition of benzodiazepine receptor

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