10493-27-3

Basic information

• Product Name: BUTTPARK 21\02-64
• Synonyms: BUTTPARK 21\02-64;5-(3,4-Dimethoxy-phenyl)-2H-tetrazole
• CAS NO: 10493-27-3
• Molecular Formula: C₉H₁₀N₄O₂
• Molecular Weight: 206.2013
• Mol File: 10493-27-3.mol
• Article Data: 10

Chemical Properties

• Melting Point: 206-207 °C(Solv: ethanol (64-17-5))
• Boiling Point: 390.1±52.0 °C(Predicted)
• Appearance: /
• Density: 1.283±0.06 g/cm3(Predicted)
• PKA: 4.24±0.10(Predicted)
• CAS DataBase Reference: BUTTPARK 21\02-64(CAS DataBase Reference)
• NIST Chemistry Reference: BUTTPARK 21\02-64(10493-27-3)
• EPA Substance Registry System: BUTTPARK 21\02-64(10493-27-3)

Safety Data

• Hazardous Substances Data: 10493-27-3(Hazardous Substances Data)

Upstream product

• 2024-83-1 veratronitrile 
• 2169-98-4 3,4-Dimethoxy-benzaldehyde oxime 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Downstream Products

• 91759-56-7 4-(2H-Tetrazol-5-yl)-benzene-1,2-diol 
• 173309-46-1 3-[5-(3,4-Dimethoxy-phenyl)-tetrazol-2-yl]-1-(4-methoxy-phenyl)-propan-1-one 
• 1234570-02-5 5-(3,4-dimethoxyphenyl)-2-[7-[5-(3,4-dimethoxyphenyl)tetrazol-1-yl]heptyl]tetrazole 
• 94772-01-7 C₁₈H₁₇ClN₈O₅S 
• 94772-00-6 C₁₈H₁₈N₈O₅S 
• 94772-07-3 [5-(3,4-Dimethoxy-phenyl)-tetrazol-2-yl]-acetic acid [1-(2,4,6-trimethoxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 94771-97-8 C₁₉H₂₁N₇O₄S 
• 94771-98-9 C₂₀H₂₃N₇O₄S 
• 94771-99-0 C₁₈H₁₈ClN₇O₃S 
• 94771-95-6 C₁₉H₂₁N₇O₃S 
• 94771-96-7 C₁₉H₂₁N₇O₃S 
• 94771-94-5 4-Phenyl-1-<5-(3,4-dimethoxyphenyl)tetrazol-2-yl-acetyl>thiosemicarbazide 
• 94772-06-2 [5-(3,4-Dimethoxy-phenyl)-tetrazol-2-yl]-acetic acid [1-(3-hydroxy-4-methoxy-phenyl)-meth-(E)-ylidene]-hydrazide 
• 94772-05-1 5-(3,4-Dimethoxyphenyl)tetrazole-2-acetic acid (2-methoxy-benzylidene)hydrazide 

Relevant articles and documents

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RETRACTED ARTICLE: Antiamoebic activity of synthetic tetrazoles against Acanthamoeba castellanii belonging to T4 genotype and effects of conjugation with silver nanoparticles

Acanthamoeba causes diseases such as Acanthamoeba keratitis (AK) which leads to permanent blindness and granulomatous Acanthamoeba encephalitis (GAE) where there is formation of granulomas in the brain. Current treatments such as chlorhexidine, diamidines

Diisopropylethylammonium acetate (DIPEAc): An efficient and recyclable catalyst for the rapid synthesis of 5-substituted-1H-tetrazoles

A simple and efficient protocol developed for the synthesis of 5-substituted 1H-tetrazole derivatives through [2+3] cycloaddition reaction between benzonitriles and sodium azide using diisopropylethylammonium acetate as a recyclable reaction medium is described. The reactions proceed well at 80 °C and provide the corresponding tetrazoles in good to excellent yields (up to 94% yield). Developed method has notable advantages, such as simple and mild conditions, easy workup, reusability with consistent catalytic activity, and safer alternative to hazardous, corrosive conventional Lewis acid catalysts.

One-step synthesis of 5-substituted 1 H -Tetrazoles from an aldehyde by reaction with acetohydroxamic acid and sodium azide under Bi(OTf)3 Catalysis

An efficient one-step method for the synthesis of 5-substituted 1H-tetrazoles from aldehydes by reaction with acetohydroxamic acid and sodium azide using bismuth(III) triflate as the catalyst is described. Georg Thieme Verlag Stuttgart · New York.