1049319-06-3Relevant academic research and scientific papers
Chemoenzymatic synthesis of CMP-N-acetyl-7-fluoro-7-deoxy-neuraminic acid
Hartlieb, Sina,Guenzel, Almut,Gerardy-Schahn, Rita,Muenster-Kuehnel, Anja K.,Kirschning, Andreas,Draeger, Gerald
, p. 2075 - 2082 (2008/12/21)
7-Fluoro sialic acid was prepared and activated as cytidine monophosphate (CMP) ester. The synthesis started with d-glucose, which was efficiently converted into N-acetyl-4-fluoro-4-deoxy-d-mannosamine. Aldolase catalyzed transformation yielded the corres
