1049706-68-4

Basic information

• Product Name: 3-nitro-2-phenylpyridine N-oxide
• Synonyms: 3-nitro-2-phenylpyridine N-oxide
• CAS NO: 1049706-68-4
• Molecular Weight: 216.196
• Mol File: 1049706-68-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-nitro-2-phenylpyridine N-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: 3-nitro-2-phenylpyridine N-oxide(1049706-68-4)
• EPA Substance Registry System: 3-nitro-2-phenylpyridine N-oxide(1049706-68-4)

Safety Data

• Hazardous Substances Data: 1049706-68-4(Hazardous Substances Data)

Upstream product

• 98-80-6 phenylboronic acid 
• 134896-35-8 2-phenyl-3-nitropyridine 

Downstream Products

• 1049706-69-5 2-phenyl-3-nitro-6-chloropyridine 
• 1344663-83-7 6-(2-cyanophenyl)-3-nitro-2-phenylpyridine-1-oxide 
• 1344663-84-8 6-(2-(methoxycarbonyl)phenyl)-3-nitro-2-phenylpyridine-1-oxide 
• 1344663-86-0 6-ethyl-3-nitro-2-phenylpyridine-1-oxide 
• 1344663-79-1 3-nitro-2,6-diphenylpyridine-1-oxide 
• 1344663-80-4 3-nitro-2-phenyl-6-p-tolylpyridine-1-oxide 
• 1344663-88-2 6-cyclohexyl-3-nitro-2-phenylpyridine-1-oxide 
• 1344663-85-9 6-methyl-3-nitro-2-phenylpyridine-1-oxide 
• 1344663-87-1 6-butyl-3-nitro-2-phenylpyridine-1-oxide 
• 1344663-81-5 6-(naphthalen-1-yl)-3-nitro-2-phenylpyridine-1-oxide 
• 1344663-89-3 6-tert-butyl-3-nitro-2-phenylpyridine-1-oxide 
• 1344663-82-6 3-nitro-2-phenyl-6-(thiophen-2-yl)pyridine-1-oxide 

Relevant articles and documents

Facile one-pot direct arylation and alkylation of nitropyridine N -oxides with grignard reagents

Facile arylation and alkylation of nitropyridine N-oxides were developed through the reactions of Grignard reagents with nitropyridine N-oxides. For the same 4-nitropyridine N-oxide, arylation occurred at the 2- (or 6-) position, whereas alkylation occurred at the 3-position in an adjustably site-selective manner. The cooperative action of the two groups was discovered in the reactions of 3-nitropyridine N-oxides. This protocol can find wide applications in building various pyridine compounds as illustrated in total syntheses of Emoxipin and Caerulomycin A and E.