104971-13-3Relevant academic research and scientific papers
A NEW SYNTHESIS OF 2-SUBSTITUTED BENZOFURANS AND BENZOTHIOPHENS: NOVEL FRAGMENTATION REACTIONS OF SIMPLE ALKYL GROUPS
Aitken, R. Alan,Burns, Graham
, p. 3717 - 3718 (2007/10/02)
Flash vacuum pyrolysis of (2-methoxy- and (2-methylthiobenzoyl)alkylidenetriphenylphosphoranes results in loss of Ph3PO and methyl radical; cyclisation of the resulting radical intermediates leads to benzofurans and benzothiophens in which the 2-substituents have undergone novel fragmentation processes.
A Versatile Two-Stage Synthesis of 2-Substituted Benzofurans from (2-Methoxyphenyl)ethynes
Buckle, Derek, R.,Rockell, Caroline J. M.
, p. 2443 - 2446 (2007/10/02)
(2-Methoxyphenyl)ethynes react with aryl or alkyl halides to give disubstituted alkynes which are converted into the corresponding 2-substituted benzofurans on treatment with lithium iodide in 2,4,6-trimethylpyridine.
