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(E)-1-(3-Chloro-2-hydroxy-phenyl)-3-(5-nitro-furan-2-yl)-propenone, also known as EF-31, is a chemical compound with potential therapeutic properties. It has been studied for its anti-inflammatory and anticancer activities. EF-31 has been found to inhibit the nuclear factor-kappaB (NF-κB) pathway, which is involved in inflammation and cancer progression.

104971-95-1

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104971-95-1 Usage

Uses

Used in Pharmaceutical Industry:
(E)-1-(3-Chloro-2-hydroxy-phenyl)-3-(5-nitro-furan-2-yl)-propenone is used as a potential anti-cancer agent for the treatment of prostate cancer. It has shown promising results in preclinical studies, making it a potential drug candidate for the treatment of various inflammatory and cancerous conditions.
Used in Research and Development:
(E)-1-(3-Chloro-2-hydroxy-phenyl)-3-(5-nitro-furan-2-yl)-propenone is used as a subject of research to further understand its pharmacological properties and potential applications in treating various inflammatory and cancerous conditions. Further research is warranted to fully explore its therapeutic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 104971-95-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,4,9,7 and 1 respectively; the second part has 2 digits, 9 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 104971-95:
(8*1)+(7*0)+(6*4)+(5*9)+(4*7)+(3*1)+(2*9)+(1*5)=131
131 % 10 = 1
So 104971-95-1 is a valid CAS Registry Number.

104971-95-1Downstream Products

104971-95-1Relevant academic research and scientific papers

2'-Hydroxychalcone Analogs of 5-Nitrofurfural and Their Antibacterial Activity

Rao, Chebrolu Papa,Sundaramurthy, V.

, p. 447 - 448 (2007/10/02)

2-Hydroxyacetophenones (I) react with 5-nitrofurfurals (II;X=O) under acid-catalysed conditions to give 2'-hydroxychalcone analogs (III).None of these compounds (III) is found to exhibit significant antibacterial and antifungal activities except 1-(2-hydroxyphenyl)-3-(5-nitro-2-furyl)2-propen-1-one (IIIa) which shows 100percent inhibition against A. niger at 10 ppm concentration.

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