698-63-5 Usage
Description
Nitrofuran carboxaldehyde (NFC) is used to synthesize
many drugs and chemicals such as nifuraldezone, puraguanidine,
nifuratrone, furmethoxadone, etc. Furfural the
main structure of NFC was determined many years ago to be
a byproduct of formic acid synthesis. Furfural is produced
from agricultural byproducts such as sugarcane bagasse and
corncobs.
Chemical Properties
Yellow to brown crystalline low melting solid
Uses
Different sources of media describe the Uses of 698-63-5 differently. You can refer to the following data:
1. NFC and its derivatives have antibacterial and antifungal
activities. They destroy both gram-positive and gram-negative
organisms such as Staphylococcus aureus, Salmonella schotmuelleri,
Pseudomonas aeruginosa, Proteus vulgaris, Escherichia coli, and
Streptococcus pyogenes. They may be used as antibacterial agents
in a prophylactic manner, for example, in cleaning and disinfecting
products. This compound also has antitrichomonal
and antifungal activities.
2. 5-Nitro-2-furaldehyde was used in the synthesis of a series of 4-(5-nitrofuran-2-yl)prop-2-en-1-one derivatives. . It was also used in the synthesis of modified mesoporous silica (MCM-41). 5-Nitrofurfural can be commonly used as pharmaceutical intermediates.
Toxicity evaluation
NFC inhibits the uptake of oxygen and disrupts cellular respiration
within mitochondria. NFC and other nitrofurans are
relatively potent inhibitors of monoamine oxidase enzyme in
mammalian and avian species.
Check Digit Verification of cas no
The CAS Registry Mumber 698-63-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 6,9 and 8 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 698-63:
(5*6)+(4*9)+(3*8)+(2*6)+(1*3)=105
105 % 10 = 5
So 698-63-5 is a valid CAS Registry Number.
InChI:InChI=1/C5H3NO4/c7-3-4-1-2-5(10-4)6(8)9/h1-3H
698-63-5Relevant articles and documents
An efficient microwave-assisted method to obtain 5-nitrofurfural without solvents on mineral solid supports
Perez, Eduardo R.,Marrero, Alma L.,Perez, Rolando,Autie, Miguel A.
, p. 1779 - 1782 (1995)
5-nitrofurfural (5-NF) was quantitatively prepared by deacetylation of its geminal diacetate on K10 Montmorillonite under microwave irradiation without solvent.
Thermally Sensitive Protecting Groups for Cysteine, and Manufacture and Use Thereof
-
Paragraph 0092-0093, (2021/02/12)
In a preferred embodiment, there is provided a protecting group for protecting the thiol side chain of a cysteine residue, the protecting group comprising a Diels-Alder cycloadduct of a furan and a maleimide, and optionally, a linker interposed between the thiol side chain and the Diels-Alder cycloadduct.
Method for synthesizing furacilin under catalysis of supported catalyst
-
, (2018/06/26)
The invention discloses a method for synthesizing furacilin under catalysis of a supported catalyst and belongs to the field of chemical synthesis. A 5-nitrofurfural intermediate is synthesized from furfuryl alcohol used as a raw material through steps of esterification, nitration, deprotection, oxidation and the like, and then, 5-nitrofurfural and semicarbazide are subjected to a condensation reaction under the catalytic action of the supported catalyst CuO/CNTs to produce furacilin. The method is simple to operate, the adopted catalyst has the characteristics of being non-toxic, easy to remove and renewable, and the product yield is high.