104971-96-2Relevant academic research and scientific papers
2'-Hydroxychalcone Analogs of 5-Nitrofurfural and Their Antibacterial Activity
Rao, Chebrolu Papa,Sundaramurthy, V.
, p. 447 - 448 (2007/10/02)
2-Hydroxyacetophenones (I) react with 5-nitrofurfurals (II;X=O) under acid-catalysed conditions to give 2'-hydroxychalcone analogs (III).None of these compounds (III) is found to exhibit significant antibacterial and antifungal activities except 1-(2-hydroxyphenyl)-3-(5-nitro-2-furyl)2-propen-1-one (IIIa) which shows 100percent inhibition against A. niger at 10 ppm concentration.
