1049752-03-5

Basic information

• Product Name: 5-methyl-2-(6-methyl-4-oxoquinazolin-3(4H)-yl)benzoic acid
• Synonyms: 5-methyl-2-(6-methyl-4-oxoquinazolin-3(4H)-yl)benzoic acid
• CAS NO: 1049752-03-5
• Molecular Weight: 294.31
• Mol File: 1049752-03-5.mol

Chemical Properties

• CAS DataBase Reference: 5-methyl-2-(6-methyl-4-oxoquinazolin-3(4H)-yl)benzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-2-(6-methyl-4-oxoquinazolin-3(4H)-yl)benzoic acid(1049752-03-5)
• EPA Substance Registry System: 5-methyl-2-(6-methyl-4-oxoquinazolin-3(4H)-yl)benzoic acid(1049752-03-5)

Safety Data

• Hazardous Substances Data: 1049752-03-5(Hazardous Substances Data)

Upstream product

• 2941-78-8 2-Amino-5-methylbenzoic acid 
• 149-73-5 trimethyl orthoformate 
• 122-51-0 orthoformic acid triethyl ester 

Relevant articles and documents

Silver-Mediated Oxidative Decarboxylative Intramolecular Asymmetric Radical Cyclization (Csp3-Csp2) via Memory of Chirality: Access to Circumdatin Alkaloids

A novel silver-mediated oxidative decarboxylative intramolecular asymmetric radical cyclization has been developed to form a Csp3-Csp2 bond via memory of chirality. The application of the process has been demonstrated for the synthesis of the circumdatin class of alkaloids in high enantiopurity with retention of the configuration. The developed protocol is mild and works with an inexpensive silver catalyst in the absence of ligand, base, or additives. The involvement of a monoradical in the reaction has been established by trapping the radical intermediate.

Synthesis of 3-aryl-4(3H)-quinazolinones from anthranilic acids and triethyl orthoformate

A one-step, convenient approach to the synthesis of 3-aryl-4(3H)- quinazolinones by the reaction of anthranilic acid with triethyl orthoformate in the presence of a catalytic amount of concentrated sulfuric acid has been developed. The possible reaction pathway was proposed. Copyright Taylor & Francis Group, LLC.