104990-48-9

Upstream product

• 105492-43-1 4-(2-oxo-2-phenylethyl)-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 70-11-1 α-bromoacetophenone 
• 5466-88-6 3,4-dihydro-3-oxo-2H-1,4-benzoxazine 
• 31507-30-9 2-(2-nitrophenoxy)acetonitrile 
• 88-75-5 2-hydroxynitrobenzene 

Downstream Products

• 137668-04-3 1-bromo-2-phenyl-4H-imidazo<2,1-c><1,4>benzoxazine 
• 137668-17-8 1-nitro-2-phenyl-4H-imidazo<2,1-c><1,4>benzoxazine 

Relevant academic research and scientific papers

A simple and facile route for the synthesis of 2H-1,4-benzoxazin-3-(4H)- ones via reductive cyclization of 2-(2-nitrophenoxy)acetonitrile adducts in the presence of Fe/acetic acid

A simple route for the synthesis of 1,4-benzoxazin-3-(4H)-ones is described herein. This method involves the reductive cyclization of 2-(2-nitrophenoxy) acetonitrile adducts in the presence of Fe/acetic acid in good to excellent yields. This system was compatible with various other functional groups.

A Facile Synthesis of 4H-Imidazo-benzoxazines

A facile two-step synthesis of 2-(CH3/aryl)-8-(H/CH3/Cl) substituted 4H-imidazobenzoxazines(4) is described.N-Alkylation of 2H-1,4-benzoxazin-3(4H)-ones (1) with chloroacetone or ω-bromoacetophenones (5) results in 4-(2-oxopropyl/arylethyl)-2H