1049974-35-7

Basic information

• Product Name: 2-(N-tert-butylamino)-3'-bromopropiophenone
• Synonyms: 2-(N-tert-butylamino)-3'-bromopropiophenone
• CAS NO: 1049974-35-7
• Molecular Weight: 284.196
• Mol File: 1049974-35-7.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 349.7±27.0 °C(Predicted)
• Density: 1.241±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 2-(N-tert-butylamino)-3'-bromopropiophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-tert-butylamino)-3'-bromopropiophenone(1049974-35-7)
• EPA Substance Registry System: 2-(N-tert-butylamino)-3'-bromopropiophenone(1049974-35-7)

Safety Data

• Hazardous Substances Data: 1049974-35-7(Hazardous Substances Data)

Usage

Molecular Structure

A chemical compound with a tert-butylamino group and a bromine substituent attached to a propiophenone derivative.

Usage

Commonly used in research and pharmaceutical applications as a versatile building block for the synthesis of various bioactive compounds.

Potential

Has potential as a reagent in organic chemistry and as a precursor in the creation of new drugs and pharmaceuticals.

Safety Precautions

Handle with caution and follow safety protocols due to potential health hazards and environmental impact.

Upstream product

• 76650-08-3 2-Bromo-3'-bromopropiophenone 
• 75-64-9 tert-butylamine 
• 535-80-8 3-chlorobenzoate 
• 766-84-7 3-chloro-benzonitrile 
• 19829-31-3 1-(3-bromophenyl)-1-propanone 

Downstream Products

• 1193779-17-7 2-(N-tert-butylamino)-3'-bromopropiophenone fumarate 

Relevant articles and documents

MONOAM1NE REUPTAKE INHIBITORS

The invention provides bupropion analogue compounds capable of inhibiting the reuptake of one or more monoamines. The compounds may selectively bind to one or more monoamine transporters, including those for dopamine, norepinephrine,and serotonin. Such compounds may be used to treat conditions that are responsive to inhibition of the reuptake of monoamines, including addiction, depression, and obesity

Synthesis and evaluation of the anticonvulsant activity of a series of 2-amino-1-phenyl-1-propranols derived from the metabolites of the antidepressant bupropion

A series of 2-amino-1-phenyl-1-propanols that are structurally related to known metabolites of bupropion, 1 (Wellbutrin) were synthesized and evaluated as potential anticonvulsants. The (R*,R*)-2-tert-butylamino-1-(3-trifluoromethylphenyl) propanol 20 had an ED50 of 16.5 ± 2.8 mg/kg ip in mice in the maximal electroshock screen and was chosen for further evaluation.