105015-84-7

Upstream product

• 461-89-2 6-azauracil 
• 53403-36-4 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-arabinofuranose 
• 99395-04-7 1-O-acetyl-2,3,5-tri-O-benzoyl-D-xylofuranose 
• 17331-61-2 3,5-bis(trimethylsilyloxy)-1,2,4-triazine 
• 6974-32-9 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose 

Relevant academic research and scientific papers

4-alkylated 2-(2,3,5-tri-O-acyl-β-D-ribofuranosyl)- and 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)-1,2,4-triazine-3,5-diones

The alkylation of 2-(2,3,5-tri-O-acyl-β-D-ribofuranosyl)- and 2-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)- 1,2,4-triazine-3,5-diones with benzyl halides afforded the corresponding 4-benzyl derivatives whose structure was determined by spectral methods, including X-ray analysis. Some of the synthesized compounds were tested for antibacterial and antitumor activity.

An economical synthesis of D- and L-pyrimidine arabinoand ribonucleosides

The one-step synthesis of several β-D/L-arabino- and ribonucleosides was performed in good yields under reflux or microwave-assisted fusion method. A comparison of the two methods showed that better yields were obtained using the reflux conditions. Copyright Taylor and Francis Group, LLC.

A procedure for facile synthesis of nucleosides using N, O-Bistrimethyl- silylacetamide in the presence of natural phosphate coated with potassium iodide

Several α-D/L-arabino and β-D/L- xylonucleosides were synthesized in good yields under mild conditions by N-glycosylation of 1-O-acetyl D/L- arabino, and xylofuranose, with silylated nucleobases (uracil, thymine and 6- azauracil) in acetonitrile using natural phosphate (NP) coated with potassium iodide in BSA as catalyst.

TRIMETHYLIODOSILANE IN THE GLYCOSYLATION OF 5-SUBSTITUTED 6-AZAURACILS

Intermediate quaternary salts of heterocycles with trimethyliodosilane are formed in glycosylation of 2,4-bistrimethylsilylized 5-substituted 6-azauracils with the participation of trimethyliodosilane as condensing medium.