Cas 1050206-92-2,(1R,5R,6S,8R)-3,3-dimethyl-6-(p-trifluoroacetylaminophenyl)-6-(2'-propenyl)-8-(tert-butyldiphenylsilyloxymethyl)-2,4,7-trioxabicyclo[3.3.0]octane

1050206-92-2

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Product Name: (1R,5R,6S,8R)-3,3-dimethyl-6-(p-trifluoroacetylaminophenyl)-6-(2'-propenyl)-8-(tert-butyldiphenylsilyloxymethyl)-2,4,7-trioxabicyclo[3.3.0]octane
Synonyms: (1R,5R,6S,8R)-3,3-dimethyl-6-(p-trifluoroacetylaminophenyl)-6-(2'-propenyl)-8-(tert-butyldiphenylsilyloxymethyl)-2,4,7-trioxabicyclo[3.3.0]octane
CAS NO:1050206-92-2
Molecular Formula:
Molecular Weight: 639.787
EINECS: N/A
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Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
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Solubility: N/A
CAS DataBase Reference: (1R,5R,6S,8R)-3,3-dimethyl-6-(p-trifluoroacetylaminophenyl)-6-(2'-propenyl)-8-(tert-butyldiphenylsilyloxymethyl)-2,4,7-trioxabicyclo[3.3.0]octane(CAS DataBase Reference)
NIST Chemistry Reference: (1R,5R,6S,8R)-3,3-dimethyl-6-(p-trifluoroacetylaminophenyl)-6-(2'-propenyl)-8-(tert-butyldiphenylsilyloxymethyl)-2,4,7-trioxabicyclo[3.3.0]octane(1050206-92-2)
EPA Substance Registry System: (1R,5R,6S,8R)-3,3-dimethyl-6-(p-trifluoroacetylaminophenyl)-6-(2'-propenyl)-8-(tert-butyldiphenylsilyloxymethyl)-2,4,7-trioxabicyclo[3.3.0]octane(1050206-92-2)

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HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1050206-92-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1050206-92-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,0,2,0 and 6 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1050206-92:
(9*1)+(8*0)+(7*5)+(6*0)+(5*2)+(4*0)+(3*6)+(2*9)+(1*2)=92
92 % 10 = 2
So 1050206-92-2 is a valid CAS Registry Number.

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1050206-92-2Relevant academic research and scientific papers

Synthesis of p-amino-WNA derivatives to enhance the stability of the anti-parallel triplex

Taniguchi, Yosuke,Togo, Mieko,Aoki, Eriko,Uchida, Yuko,Sasaki, Shigeki

, p. 7164 - 7170 (2008/12/22)

We have previously developed W-shaped nucleoside analogs (WNAs) having a nucleobase and an aromatic ring for the formation of the unnatural triplex DNA. Modification of an aromatic ring of WNA is highly effective regarding the stability of the triplex DNA. In this study, we designed new WNA analogs having the p-aminobenzene as an aromatic ring, which were synthesized via the Curtius-Yamada rearrangement. Based on the evaluation of the triplex formation with p-amino-WNA-TFO, it has been shown that the amino group may produce a non-selective interaction with the phosphate backbone of the target duplexes. These results indicate that the amino modification is useful to overcome the sequence-dependence of the TFO containing WNA analogs.

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