105023-02-7Relevant articles and documents
Specific ortho-Cyanomethylation of Nitroarenes via the Vicarious Nucleophilic Substitution of Hydrogen
Makosza, Mieczyslaw,Wenaell, Maria,Golinski, Miroslaw,Kinowski, Andrzej
, p. 427 - 432 (2007/10/02)
The vicarious nucleophilic substitution of hydrogen in nitroarenes with acetonitrile derivatives XCH2CN in t-BuOK/THF base/solvent system proceeds exclusively ortho to the nitro group.Strong influence of substituents Z in 3-Z-nitrobenzene derivatives on the orientation has been observed.