1050477-72-9

Upstream product

• 4746-97-8 cyclohexanedione monoethylene ketal 
• 2393-23-9 4-methoxy-benzylamine 

Downstream Products

• 1050477-73-0 (8-benzyl-1,4-dioxaspiro[4,5]dec-8-yl)(4-methoxybenzyl)amine 
• 1050678-26-6 (8-Allyl-1,4-dioxaspiro[4.5]dec-8-yl)-(4-methoxybenzyl)amine 
• 1350894-84-6 C₂₃H₂₅N₃O₂ 
• 1350894-71-1 C₂₄H₂₄N₂O₄ 
• 218628-43-4 N-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-N-(4-methoxybenzyl)-2-(3,4-methylenedioxyphenyl)-2-(phenylseleno)acetamide 
• 218628-42-3 N-(1,4-Dioxaspiro[4.5]dec-7-en-8-yl)-N-(4-methoxybenzyl)-2-(3,4-methylenedioxyphenyl)acetamide 

Relevant academic research and scientific papers

Access to saturated fused pyrimidine derivatives via a flexible N -vinyl tertiary enamide synthesis

An array of tetrasubstituted saturated fused pyrimidines has been synthesized through two-sequential, simple, and efficient one-pot operations. The strategic utilization of the N-PMB group proved critical in the ability to construct a broad range of N-vinyl tertiary enamide starting materials. This stands as a flexible approach to functionalized pyrimidines with the capability of manipulating either ketone, acid chloride, or nitrile reaction partners. Georg Thieme Verlag Stuttgart - New York.

Spirocyclic Cyclohexane Compounds

Spirocyclic cyclohexane compounds corresponding to formula I In which R1, R2, R3 and R5 through R10 and X have defined meanings, a process for their preparation, pharmaceutical compositions containing such compounds, and the use of such spirocyclic cyclohexane compounds in the treatment and/or inhibition of pain and other conditions mediated by the ORL-1 or the ?-opioid receptor.

Spirocyclic Cyclohexane Compounds

Spirocyclic cyclohexane compounds corresponding to formula I in which R1 and R2 form a pyrrolidine ring or an azetidine ring and which exhibit increased metabolic stability, a process for producing such spirocyclic cyclohexane compou

Formal synthesis of (±)-pancracine using stereoselective radical cyclization of N-(2-cyclohexenyl)-α-aryl-α-(phenylthio)acetamide

(Me3Si)3SiH-mediated 5-exo-trig radical cyclization of N-(2-cyclohexcnyl)-α-aryl-α-(phenylthio)acetamide 19 proceeded in a stereoselective manner to give (3R*,3aS*,7aS*)-3-aryloctahydroindol-2-one 20. The product was transformed into the key intermediate 25 for the synthesis of (±)-pancracine (1), a montanine-type Amaryllidaceae alkaloid.