1050534-41-2Relevant academic research and scientific papers
Synthesis of fluorophosphonylated acyclic nucleotide analogues via copper(I)-catalyzed Huisgen 1-3 dipolar cycloaddition
Amel Diab, Sonia,Hienzch, Antje,Lebargy, Cyril,Guillarme, Stephane,Pfund, Emmanuel,Lequeux, Thierry
supporting information; experimental part, p. 4481 - 4490 (2009/12/25)
Preparation of several acyclonucleosides containing both a difluoromethylphosphonate group and a triazole moiety is described starting from a difluorophosphonosulfide. The key step of the synthesis involves a copper(I)-catalyzed Huisgen 1-3 dipolar cycloa
Efficient synthesis of fluorophosphonylated alkyles by ring-opening reaction of cyclic sulfates
Diab, Sonia Amel,Sene, Aboubacary,Pfund, Emmanuel,Lequeux, Thierry
supporting information; experimental part, p. 3895 - 3898 (2009/05/31)
(Figure Presented) Ring-opening reactions of functionalized 1,2-cyclic sulfates and oxetanes with the phosphonodifluoromethyl carbanion are reported. This approach allows an easy access to fluorinated βhydroxyphosphonates that are building blocks in the s
