1050593-75-3Relevant academic research and scientific papers
Racemic and asymmetric cobalt-catalysed reductive aldol couplings of α,β-unsaturated amides with ketones
Lumby, Ralph J.R.,Joensuu, Pekka M.,Lam, Hon Wai
, p. 7729 - 7740 (2008/12/20)
In the presence of diethylzinc as a stoichiometric reductant, substoichiometric quantities of an appropriate cobalt source catalyse diastereoselective reductive aldol coupling reactions of α,β-unsaturated amides with ketones. The use of a readily available oxazolidine as a chiral auxiliary imparts high levels of asymmetric induction in these reactions.
