105074-25-7Relevant articles and documents
2,2-Difluorovinyl Pinacolborane – A New Versatile Reagent for the Suzuki–Miyaura Reaction
Blahun, Oleksandr P.,Redka, Mykhailo O.,Voitenko, Zoia V.,Kysil, Andrii I.,Dobrydnev, Alexey V.,Grygorenko, Oleksandr O.
, p. 6417 - 6421 (2019)
A novel fluorinated reagent for the synthesis of gem-difluorostyrenes and their heterocyclic analogues – 2,2-difluorovinyl pinacolborane (CF2=CHBPin) was developed. In particular, borylation of 1,1-difluoroethylene with isopropoxy pinacolborane
Manganese-catalyzed synthesis of monofluoroalkenes: Via C-H activation and C-F cleavage
Cai, Sai-Hu,Ye, Lu,Wang, Ding-Xing,Wang, Yi-Qiu,Lai, Lin-Jie,Zhu, Chuan,Feng, Chao,Loh, Teck-Peng
supporting information, p. 8731 - 8734 (2017/08/09)
The manganese-catalyzed α-fluoroalkenylation of arenes via C-H activation and C-F cleavage has been described. This protocol provides a very useful method for the synthesis of monofluoroalkenes with predominant unconventional E-isomer selectivity which complements the existing strategies for the access to these molecular architectures. In addition, the selectivity of β-defluorination in the catalytic cycle not only determines the configurations of the products but also obviates the use of external oxidants, providing a good example in the exploitation of manganese-catalyzed redox-neutral C-H transformations.
