105099-65-8Relevant academic research and scientific papers
Nortropinyl-arylsulfonylureas as novel, reversible inhibitors of human steroid sulfatase
Nussbaumer, Peter,Geyl, Dieter,Horvath, Amarylla,Lehr, Philipp,Wolff, Barbara,Billich, Andreas
, p. 3673 - 3677 (2007/10/03)
Steroid sulfatase (STS) has emerged as an attractive target for a range of estrogen- and androgen-dependent diseases. Searching for novel chemotypes as STS inhibitors, we identified nortropinyl-arylsulfonylurea 3 as a hit from high-throughput screening. A
NMDA antagonists
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, (2008/06/13)
The present invention is directed to a new class of 4-sulfanimide-quinoline derivatives and to their use as NMDA antagonists.
