105122-39-2Relevant academic research and scientific papers
Substituent-controlled reactivity in the Nazarov cyclisation of allenyl vinyl ketones
Marx, Vanessa M.,Stoddard, Rhonda L.,Heverly-Coulson, Gavin S.,Burnell, D. Jean
, p. 8098 - 8104 (2011/09/14)
Alkyl substitution α to the ketone of an allenyl vinyl ketone enhances Nazarov reactivity by inhibiting alternative pathways involving the allene moiety and through electron donation and/or steric hindrance. This substitution pattern also accelerates Naza
Organic Syntheses via Transition Metal Complexes, 19. - β-Methylenecyclopentenones via Iron Carbonyl-Induced Cycloaddition of Alkynes to Allenes and Carbon Monoxide
Aumann, Rudolf,Weidenhaupt, Hermann-Josef
, p. 23 - 28 (2007/10/02)
From alkynes, allenes, and carbon monoxide β-methylenecyclopentenones 3 and 4 are obtained in a one-pot procedure.The reaction involves a template-induced cycloaddition via carbonyl iron complexes as intermediates.The regio- and stereoselectivity of this synthesis has been studied by means of model reactions.The fragmentation pattern observed in the mass spectrum of these compounds corresponds to the retro-synthesis.
