105176-08-7Relevant articles and documents
Synthesis of 5-, 6-, 7- and 18-mono-13C-labelled retinals
Courtin, J. M. L.,'t Lam, G. K.,Peters, A. J. M.,Lugtenburg, J.
, p. 281 - 288 (2007/10/02)
Four retinals labelled at positions 5,6,7 and 18 with 13C were obtained via simple schemes involving only a few steps with >98percent chemical purity and 92percent 13C incorporation. (5-13C)Retinal was obtained in 26percent yield from K13CN. (6-13C)- and (7-13C)Retinal were obtained in 37percent yield from (2-13C)- and (1-13C)acetonitrile, respectively, while (18-13C)retinal was obtained in 8 steps and 4percent yield starting from 13CH3I.Their 13C - 1H and 13C - i142213C NMR coupling constants were determined.
