105192-47-0Relevant academic research and scientific papers
Synthesis and antitumor activity of tropolone derivatives. 6. Structure-activity relationships of antitumor-active tropolone and 8-hydroxyquinoline derivatives
Yamato,Hishigaki,Yasumoto,Sakai,Luduena,Banerjee,Tsukagoshi,Tashiro,Tsuruo
, p. 1897 - 1900 (2007/10/02)
The bis derivative 6 of 8-hydroxyquinoline, which, like tropolones, readily forms a chelate, was synthesized and found to have high potency (dose = 12.5 mg/kg, T/C % = 164) against leukemia P388 in mice approximately equivalent to that of the bistropolone
