2403-58-9

Basic information

• Product Name: p-(diethoxymethyl)anisole
• Synonyms: p-(diethoxymethyl)anisole;Benzene, 1-(diethoxymethyl)-4-methoxy-;4-(Diethoxymethyl)anisole;1-(Diethoxymethyl)-4-methoxybenzene;Nsc20033
• CAS NO: 2403-58-9
• Molecular Formula: C₁₂H₁₈O₃
• Molecular Weight: 210.26952
• EINECS: 219-288-6
• Mol File: 2403-58-9.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 103-104°C/3.5mm
• Flash Point: 103-104°C/3.5mm
• Appearance: /
• Density: 1.06
• Refractive Index: 1.4920
• CAS DataBase Reference: p-(diethoxymethyl)anisole(CAS DataBase Reference)
• NIST Chemistry Reference: p-(diethoxymethyl)anisole(2403-58-9)
• EPA Substance Registry System: p-(diethoxymethyl)anisole(2403-58-9)

Safety Data

• Hazardous Substances Data: 2403-58-9(Hazardous Substances Data)

Usage

General Description

p-(diethoxymethyl)anisole is a chemical compound commonly used as a fragrance and flavor ingredient in various cosmetic and personal care products. It is an organic compound with a molecular formula of C12H18O3 and is derived from anisole, a naturally occurring substance found in certain plant species. This chemical is colorless and has a sweet, floral odor, making it ideal for use in perfumes and scented products. p-(diethoxymethyl)anisole is also used as a solvent and a reagent in organic chemistry reactions. However, it is important to handle this chemical with caution and follow proper safety protocols, as it can be harmful if ingested or inhaled and may cause skin and eye irritation.

InChI:InChI=1/C12H18O3/c1-4-14-12(15-5-2)10-6-8-11(13-3)9-7-10/h6-9,12H,4-5H2,1-3H3

Upstream product

• 88920-25-6 ethoxy-p-methoxyphenylacetic acid 
• 2299-73-2 N,N-bis(4-methoxybenzylidene)hydrazine 
• 64-17-5 ethanol 
• 123-11-5 4-methoxy-benzaldehyde 
• 122-51-0 orthoformic acid triethyl ester 
• 16694-46-5 ethyl formimidate hydrochloride 
• 998-30-1 Triethoxysilane 
• 104-94-9 4-methoxy-aniline 
• 104-46-1 anethole 
• 13139-86-1 4-methoxyphenyl magnesium bromide 
• 873376-62-6 triethoxyantimony 
• 36141-66-9 ethyl 2-hydroxy-2-(4-methoxyphenyl)acetate 
• 105-13-5 4-Methoxybenzyl alcohol 

Downstream Products

• 119093-27-5 methyl 2-deoxy-4,6-O-para-methoxybenzylidene-β-D-lyxo-hexoside 
• 92594-55-3 [Ethoxy-(4-methoxy-phenyl)-methyl]-phosphonic acid diethyl ester 
• 2278-78-6 1,1,3-Triaethoxy-3-(p-methoxyphenyl)-propan 
• 23837-10-7 ((4-methoxyphenyl)methylene)bis(phenylsulfane) 
• 123-11-5 4-methoxy-benzaldehyde 
• 6712-20-5 2-(4-methoxyphenyl)-[1,3]dithiolane 
• 14674-38-5 N-(4-methoxybenzylidene)-p-toluenesulfonamide 
• 83726-05-0 1-Diethoxymethyl-4-methoxy-cyclohexa-1,4-diene 
• 64-17-5 ethanol 
• 82519-90-2 8-methoxy-3-(4-methoxyphenyl)-1H-naphtho<2,1-d><1,3>dioxin 
• 95201-82-4 1',2'-dihydro-6,8'-dimethoxy-spironaphtho<2,1-b>pyran>-2-one 
• 76680-51-8 C₂₄H₂₆N₄O₃S₂ 
• 111514-34-2 2-(p-methoxyphenyl)-5-phenyl-5-thio-1,3,5-dioxaphosphorinane 
• 97056-54-7 5-ethoxy-5-(4-methoxyphenyl)-3-methyl-2-pentenal 

Relevant articles and documents

Conjugate addition of acetal-derived benzyl radicals generated from low-valent titanium-mediated CO bond cleavage

A new method for the generation of benzyl radicals from acetals via low-valent titanium-mediated homolytic CO bond cleavage is presented. The low cost and availability of the developed titanium reagent enable efficient access to α-alkoxy carbon radical species via the developed reaction.

Tropylium salts as efficient organic Lewis acid catalysts for acetalization and transacetalization reactions in batch and flow

Acetalization reactions play significant roles in the synthetically important masking chemistry of carbonyl compounds. Herein we demonstrate for the first time that tropylium salts can act as organic Lewis acid catalysts to facilitate acetalization and transacetalization reactions of a wide range of aldehyde substrates. This metal-free method works efficiently in both batch and flow conditions, prompting further future applications of tropylium organocatalysts in green synthesis.

Development of a novel Br?nsted acid UiO-66 metal-organic framework catalyst by postsynthetic modification and its application in catalysis

A novel Br?nsted acid derived metal-organic framework (MOF) has been developed to serve as an efficient heterogeneous catalyst for the acetalization and Morita-Baylis-Hillman reaction. Aromatic sulfonic acid groups were successfully incorporated to the framework of UiO-66 by post-synthetic modifications using commercially available anhydridic reagents. The UiO-66-RArSO3H Br?nsted acid catalyst was fully characterized using SEM, PXRD, FTIR, TGA and N2 adsorption/desorption isotherms. Furthermore, efficient acetalization and Morita-Baylis-Hillman reactions were evaluated to demonstrate the high catalytic performance of the UiO-66-RArSO3H catalyst. The UiO-66-RArSO3H catalyst is compatible with a variety of substituted substrates and can be recycled five times without a compromise in the yield or selectivity.