1051966-63-2Relevant academic research and scientific papers
NOVEL POLYSPIRANE COMPOUNDS, APPLICATION THEREOF IN THE TREATMENT OF MALARIA OR TOXOPLASMOSIS AND METHOD FOR PREPARING SAME
-
Page/Page column 33, (2010/12/29)
Novel polyspirane compounds used in the treatment of diseases involving parasites that belong to the phylum of apicomplexae, and a method for preparing the same.
Enhanced antimalarial activity of novel synthetic aculeatin derivatives
Peuchmaur, Marine,Sa?dani, Nadia,Botté, Cyrille,Maréchal, Eric,Vial, Henri,Wong, Yung-Sing
supporting information; experimental part, p. 4870 - 4873 (2009/07/25)
We report the design, synthesis, and in vitro evaluation of novel polyspirocyclic structures, inspired by the antimalarial natural products, the aculeatins. A divergent synthetic strategy was conceived for the practical supply and has allowed the discover
