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Upstream product

• 15241-32-4 1-methoxy-2-(2-nitrovinyl)benzene 
• 67-64-1 acetone 
• 3316-24-3 1-methoxy-2-((E)-2-nitrovinyl)benzene 
• 75-52-5 nitromethane 
• 60438-50-8 2-methoxybenzalacetone 

Relevant academic research and scientific papers

Concentration Effect in the Asymmetric Michael Addition of Acetone to β-Nitrostyrenes Catalyzed by Primary Amine Thioureas

Bifunctional primary amine thiourea (PAT) organocatalysts show remarkable improvement in enantioselectivity and catalytic activity (turnover frequency) in the asymmetric Michael addition of acetone to β-nitrostyrenes upon dilution. Mechanistic investigati

Optically Active 4-Substituted 5-Nitropentan-2-ones: Valuable Chiral Building Blocks for the Stereocontrolled Construction of Spiro-Pyrazolone Scaffolds with Five Contiguous Stereogenic Centers

The application of readily available optically active 4-substituted 5-nitropentan-2-ones as chiral building blocks in the stereocontrolled construction of spiro-pyrazolone scaffolds was investigated. In the presence of 1,8-diazabicyclo[5.4.0]undec-7-ene (

New simple primary amine-thiourea organocatalysts and their application in asymmetric conjugate addition

A kind of simple primary amine-thiourea organocatalysts was developed. And their application in asymmetric conjugate addition of ketone to nitroalkene was investigated. In the presence of the new primary amine-thiourea, the conjugate addition of ketone to

Asymmetric synthesis of tetrahydroquinolines through supramolecular organocatalysis

Functionalized chiral tetrahydroquinolines were synthesized through supramolecular organocatalysis using quinidine-NH-thiourea 3c/l-phenylalanine 4i followed by reductive amination from the simple substrates. the Partner Organisations 2014.

Organocatalyzed Michael addition reaction by novel (2 R,3a S,7a S)-octa-hydroindole-2-carboxylic acid, a new fused proline

We present here the results obtained in our study on organocatalytic enantioselective Michael addition reaction of acetone to different nitroolefines using (2R,3aS,7aS)-octahydroindole-2-carboxylic acid [(R,S,S)-Oic] as a new and suitable catalyst for thi

Asymmetric multifunctional organocatalytic Michael addition of nitroalkanes to α,β-unsaturated ketones

Cinchona alkaloid derived primary amine thioureas organocatalyzed Michael addition of nitroalkanes to enones in good yield and up to 98% ee and offered a new way to construct quaternary stereocenters from enones and nitroalkanes. The Royal Society of Chem

A novel bifunctional sulfonamide primary amine-catalyzed enantioselective conjugate addition of ketones to nitroolefins

The enantioselective conjugate addition of a variety of ketones to nitroolefins has been developed. The process is efficiently catalyzed by a novel bifunctional sulfonamide primary amine in good yields and with good levels of enantioselectivity.