105219-41-8

Basic information

• Product Name: Benzene, 1,3-difluoro-5-(3-isothiocyanatopropyl)-
• CAS NO: 105219-41-8
• Molecular Formula: C10H9F2NS
• Molecular Weight: 213.251
• Mol File: 105219-41-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzene, 1,3-difluoro-5-(3-isothiocyanatopropyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,3-difluoro-5-(3-isothiocyanatopropyl)-(105219-41-8)
• EPA Substance Registry System: Benzene, 1,3-difluoro-5-(3-isothiocyanatopropyl)-(105219-41-8)

Safety Data

• Hazardous Substances Data: 105219-41-8(Hazardous Substances Data)

Upstream product

• 105219-40-7 3-(3,5-difluorophenyl)-1-propylamine 
• 463-71-8 thiophosgene 
• 60-29-7 diethyl ether 

Relevant articles and documents

4-Aralkyl-5-substituted-1,2,4-triazole-5-thiols

Compounds of formula (I) and pharmaceutically acceptable salts thereof are described in which, n is 0 to 5; X1 to X5 are any accessible combination of hydrogen, halogen, C1 6alkyl, C1 6alkoxy, cyano, nitro, SONH2, SO2NH2, SO2CH3, SO2CH2F, SO2CHF2, SO2CF3, CF3, CHO, OH, CH2OH, CO2H, or CO2CpH2p+1wherein p is 1 to 4; R1 is phenyl substituted by X1 to X5, C1 4alkyl, C3 6cycloalkyl, or an arylC1 4alkyl group substituted by X1 to X5; R2 is hydrogen, C1 4alkyl or (CH2)m-CO2R3; m is 0 to 5; and R3 is H or C1 4alkyl. These compounds are dopamine-β-hydroxylase inhibitors. Pharmaceutical compositions are described as are methods of use. Processes for the preparation of these compounds are described.