10522-05-1Relevant academic research and scientific papers
Efficient and regioselective ring-opening of epoxides with carboxylic acid catalyzed by graphite oxide
Mirza-Aghayan, Maryam,Tavana, Mahdieh Molaee,Niazi, Elaheh Golam Alipour,Boukherroub, Rabah
, p. 532 - 538 (2020/07/17)
An efficient, simple and regioselective ring-opening reaction of epoxides with various carboxylic acids under metal-free conditions is reported. The ring-opening of epoxides takes place in the presence of graphite oxide as an efficient and available catalyst to produce the corresponding 2-hydroxy monoester and 1,2-diester derivatives in good yields. Regioselective attack of the nucleo-phile, short reaction times, metal-free conditions and reusability of catalyst are among the advantages of the present protocol.
PPL-CATALYZED RESOLUTION OF 1,2- AND 1,3-DIOLS IN METHYL PROPIONATE AS SOLVENT. AN APPLICATION OF THE TANDEM USE OF ENZYMES.
Janssen, A. J. M.,Klunder, A, J. H.,Zwanenburg, B.
, p. 7409 - 7416 (2007/10/02)
The Porcine Pancreatic Lipase (PPL)-catalyzed transesterification of 1-phenyl-1,2-ethanediol 1, 2-phenyl-1,2-propanediol 2, 1,2-decanediol 3, 1,2-pentanediol 4, 1,2-butanediol 5, 1,2-propanediol 6 and 1,3-butanediol 7 in methyl propionate as solvent was evaluated.In all substrates, the primary hydroxy group is esterified exclusively.The enantioselectivity displayed in this PPL-catalyzed reaction is moderate.The enantiomeric excess of diol (-)-1 is enhanced by subjecting propionate (-)-8, with a moderate ee (obtained by a PPL-catalyzed esterification of racemic 1 in methyl propionate), to an enzyme-catalyzed hydrolyis (tandem principle).
OXIDATION OF ISOXAZOLINES BY PERACIDS - A USEFUL ROUTE TO β-HYDROXY KETONES AND ACYLATED DIOLS
Park, Pyeong-uk,Kozikowski, Alan P.
, p. 6703 - 6706 (2007/10/02)
A method for bringing about the ring cleavage of isoxazolines by the use of peracids is described.
