105220-77-7Relevant academic research and scientific papers
THE SYNTHESIS OF 5,6-CYCLOPROPANOCHOLESTANES WITH OXYGEN FUNCTIONS IN POSITIONS 3 AND 7
Kohout, Ladislav
, p. 429 - 435 (2007/10/02)
The Simmons-Smith methylenation of the double bond in 3β-acetoxycholest-5-en-7-ols takes place selectively under formation of an adduct the configuration of which is determined by the configuration of the 7-hydroxyl group: 7β-alcohol IV gave 5β,6β-cyclopropane derivative VI, 7α-alcohol V gave 5α,6α-cyclopropane derivative VIII.On photochemically initiated cyclization of 3β-acetoxy-B-homo-5-en-7a-one (XIII) we obtained the product with an α-cyclopropane ring exclusively, i.e. 3β-acetoxy-5,6α-cyclopropano-5α-cholestan-7-one (XII)-
