1052210-00-0 Usage
General Description
(5R)-5-(phenylMethyl)-3-Morpholinone, also known as PMPM, is a chemical compound with the molecular formula C12H15NO2. It is a morpholine derivative with a phenylmethyl group attached to the carbon at position 5. PMPM is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It possesses a chiral center at the fifth position, giving rise to its (5R) configuration. PMPM has been studied for its potential biological activities, including its role as an inhibitor of acetylcholinesterase, an enzyme involved in the breakdown of the neurotransmitter acetylcholine. (5R)-5-(phenylMethyl)-3-Morpholinone is important in medicinal chemistry and drug discovery efforts due to its potential as a pharmacologically active molecule.
Check Digit Verification of cas no
The CAS Registry Mumber 1052210-00-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,2,2,1 and 0 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1052210-00:
(9*1)+(8*0)+(7*5)+(6*2)+(5*2)+(4*1)+(3*0)+(2*0)+(1*0)=70
70 % 10 = 0
So 1052210-00-0 is a valid CAS Registry Number.
1052210-00-0Relevant articles and documents
4-(1,3-Thiazol-2-yl)morpholine derivatives as inhibitors of phosphoinositide 3-kinase
Alexander, Rikki,Balasundaram, Ahrani,Batchelor, Mark,Brookings, Daniel,Crepy, Karen,Crabbe, Tom,Deltent, Marie-France,Driessens, Frank,Gill, Andrew,Harris, Sue,Hutchinson, Gillian,Kulisa, Claire,Merriman, Mark,Mistry, Prakash,Parton, Ted,Turner, James,Whitcombe, Ian,Wright, Sara
scheme or table, p. 4316 - 4320 (2009/04/06)
4-(1,3-Thiazol-2-yl)morpholine derivatives have been identified as potent and selective inhibitors of phosphoinositide 3-kinase. The SAR data of selected examples are presented and the in vivo profiling of compound 18 is shown to demonstrate the utility of this class of compounds in xenograft models of tumor growth.