1052240-89-7Relevant academic research and scientific papers
Enantioselective synthesis of anti-β-substituted γ,δ- unsaturated amino acids: A highly selective asymmetric thio-Claisen rearrangement
Liu, Zhihua,Qu, Hongchang,Gu, Xuyuan,Min, Byoung J.,Nyberg, Joel,Hruby, Victor J.
supporting information; experimental part, p. 4105 - 4108 (2009/05/30)
(Chemical Equation Presented) A novel synthesis of optically active anti-β-substituted γ,δ-unsaturated amino acids via a thio-Claisen rearrangement has been achieved. A 2,5-diphenylpyrrolidine was used as a (C2-symmetric chiral auxiliary to control the stereochemistry, giving good yields and excellent diastereoselectivities and enantioselectivities.
