105251-52-3 Usage
Uses
Used in Chemistry and Biochemistry Research:
(1S, 9S)-(-)-1,9-BIS[(TERT-BUTYLDIMETHYLSILYLOXY)METHYL]-5-CYANOSEMICORRIN is used as a research compound for studying cobalt-based enzymatic processes and the role of vitamin B12 in various biological systems. Its unique structure and functional groups allow for the investigation of its interactions with enzymes and other biomolecules, contributing to a deeper understanding of the mechanisms involved in these processes.
Used in Pharmaceutical Development:
In the pharmaceutical industry, (1S, 9S)-(-)-1,9-BIS[(TERT-BUTYLDIMETHYLSILYLOXY)METHYL]-5-CYANOSEMICORRIN is used as a starting material or intermediate in the synthesis of vitamin B12 analogues and other cobalt-containing drugs. Its unique structure and functional groups can be modified to create new compounds with potential therapeutic applications, such as improved absorption, targeted delivery, or enhanced stability.
Used in Analytical Chemistry:
(1S, 9S)-(-)-1,9-BIS[(TERT-BUTYLDIMETHYLSILYLOXY)METHYL]-5-CYANOSEMICORRIN can be employed as a reference compound or standard in analytical chemistry for the development and validation of methods for the detection and quantification of cobalt-containing compounds, including vitamin B12 and its analogues. Its unique structure and functional groups make it a suitable candidate for these applications, ensuring accurate and reliable results in various analytical techniques.
Used in Material Science:
In the field of material science, (1S, 9S)-(-)-1,9-BIS[(TERT-BUTYLDIMETHYLSILYLOXY)METHYL]-5-CYANOSEMICORRIN may be utilized in the development of novel materials with specific properties, such as catalysts, sensors, or functional coatings. Its unique structure and functional groups can be exploited to create materials with tailored characteristics, such as enhanced catalytic activity, selective binding, or improved stability under various conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 105251-52-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,2,5 and 1 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 105251-52:
(8*1)+(7*0)+(6*5)+(5*2)+(4*5)+(3*1)+(2*5)+(1*2)=83
83 % 10 = 3
So 105251-52-3 is a valid CAS Registry Number.
InChI:InChI=1/C24H45N3O2Si2/c1-23(2,3)30(7,8)28-16-18-11-13-21(26-18)20(15-25)22-14-12-19(27-22)17-29-31(9,10)24(4,5)6/h18-19,26H,11-14,16-17H2,1-10H3/b21-20-/t18-,19-/m0/s1
105251-52-3Relevant articles and documents
Semicorrin Metal Complexes as Enantioselective Catalysts. Part 1. Synthesis of Chiral Semicorrin Ligands and General Concepts
Fritschi, Hugo,Leutenegger, Urs,Siegmann, Konstantin,Pfaltz, Andreas,Keller, Walter,Kratky, Christoph
, p. 1541 - 1552 (2007/10/02)
An efficient synthesis of chiral semicorrin ligands is described (see 6-9, Schemes 2 and 3).Both enantiomers are readily obtained in enantiomerically pure form starting either from D- or L-pyroglutamic acid (1).Semicorrins of this type possess several features that make them attractive ligands for enantioselective control of metal-catalyzed reactions.Their structure is characterized by C2 symmetry, a conformationally rigid ligand system, and two stereogenic centers adjacent to the coordination sphere.In a metal complex, the two substituents at the stereogenic centers shield the metal atom from two opposite directions and, therefore, are expected to have a pronounced effect on the stereochemical course of a reaction occuring in the coordination sphere.The structure of these two substituents can be easily modified in a variety of ways.A series of (semicorrinato)copper(II) complexes (see 10-14, Scheme 4) has been prepared, and in one case (14), the three-dimensional structure has been determined by X-ray analysis (Fig. 1).
