105258-93-3 Usage
Description
N-CBZ-3-OXOAZETIDINE, also known as carbobenzyloxy-3-oxoazetidine, is a chemical compound with the molecular formula C11H11NO3. It is an azetidine derivative that is widely used in organic synthesis and pharmaceutical research due to its potential pharmacological activities, such as antiviral and antitumor properties. Its unique structure allows it to be a versatile building block in the synthesis of various pharmaceutical compounds and in the preparation of peptide-based drugs. Additionally, N-CBZ-3-OXOAZETIDINE is known for its ability to form stable complexes with metal ions, making it a valuable component in metal coordination chemistry.
Uses
Used in Pharmaceutical Research:
N-CBZ-3-OXOAZETIDINE is used as a key intermediate in the synthesis of pharmaceutical compounds for its potential antiviral and antitumor properties. Its unique structure allows for the development of new drugs with improved efficacy and reduced side effects.
Used in Organic Synthesis:
N-CBZ-3-OXOAZETIDINE is used as a building block in organic synthesis for the creation of complex organic molecules. Its reactivity and stability make it a valuable component in the synthesis of various organic compounds.
Used in Peptide-based Drug Preparation:
N-CBZ-3-OXOAZETIDINE is used as a component in the preparation of peptide-based drugs due to its ability to form stable complexes with metal ions. This property enhances the stability and bioavailability of peptide-based drugs, improving their therapeutic outcomes.
Used in Metal Coordination Chemistry:
N-CBZ-3-OXOAZETIDINE is used in metal coordination chemistry for its ability to form stable complexes with metal ions. This property allows it to be employed in the development of new materials with unique properties, such as catalysts, sensors, and drug delivery systems.
Check Digit Verification of cas no
The CAS Registry Mumber 105258-93-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,2,5 and 8 respectively; the second part has 2 digits, 9 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 105258-93:
(8*1)+(7*0)+(6*5)+(5*2)+(4*5)+(3*8)+(2*9)+(1*3)=113
113 % 10 = 3
So 105258-93-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H11NO3/c13-10-6-12(7-10)11(14)15-8-9-4-2-1-3-5-9/h1-5H,6-8H2
105258-93-3Relevant articles and documents
Intramolecular N-H insertion of α-diazocarbonyls catalyzed by Cu(acac)2: An efficient route to derivatives of 3-oxoazetidines, 3-oxopyrrolidines and 3-oxopiperidines
Wang, Jianbo,Hou, Yihua,Wu, Peng
, p. 2277 - 2280 (1999)
Cu(acac)2 was found to be an efficient catalyst for the intramolecular N-H insertion by carbenoids. The competitive intramolecular C-H insertion by carbenoids is not a problem in the diazo decomposition reaction with Cu(acac)2 as catalyst. The reaction provided derivatives of 3-oxoazetidine, 3-oxopyrrolidine and 3-oxopiperidine in moderate to good yields.
Packaging comprising forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide
-
, (2016/08/29)
The invention relates to a packaging comprising a multitude (A) of at least 2 administration units comprising polymorphic trihydrated forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide; or (B) of at least 2 administration units comprising polymorphic solvated or desolvated forms of sodium salt of 4-tert-butyl-N-[4-chloro-2-(1-oxy-pyridine-4-carbonyl)-phenyl]-benzenesulfonamide.
N- (6- ( (2R,3S) -3,4-DIHYDROXYBUTAN-2-YLOXY) -2- (4 - FLUOROBENZYLTHIO) PYRIMIDIN- 4 - YL) -3- METHYLAZETIDINE- 1 - SULFONAMIDE AS CHEMOKINE RECEPTOR MODULATOR
-
, (2013/03/26)
There is provided a compound which is (a) a pyrimidine sulfonamide of formula (I) or (b) a pharmaceutically acceptable salt thereof, crystalline forms of the compound, processes for obtaining the compound, pharmaceutical intermediates used in the manufacture of the compound, and pharmaceutical compositions containing the compound. The compound is useful in the treatment of a disease/condition in which modulation of chemokine receptor activity is beneficial.
