105310-98-3Relevant academic research and scientific papers
Selective Reactions of Azide-Substituted α-Diazo Amides with Olefins and Alcohols Using Rhodium(II) Catalysts
Jeganathan, Alwarsamy,Richardson, Steward K.,Mani, Rajarathnam S.,Haley, Boyd E.,Watt, David S.
, p. 5362 - 5367 (2007/10/02)
The synthesis and addition of azide-substituted α-diazo amides such as N-(4-azidophenyl)-α-diazoacetamide and N-(4-azido-2-hydroxyphenyl)-α-diazoacetamide to olefins and alcohols using either rhodium(II) acetate or preferably rhodium(II) pivalate provided cyclopropanecarboxamides and α-alkoxy amides, respectively, without disrupting the azide functionality.These azide-bearing α-diazo amides are potentially useful in the preparation of photoaffinity cross-linking reagents for studying the mechanism of action of natural products.
