1053179-85-3Relevant academic research and scientific papers
Aminomethylpiperazines as selective urotensin antagonists
Hilfiker, Mark A.,Zhang, Daohua,Dowdell, Sarah E.,Goodman, Krista B.,McAtee, John J.,Dodson, Jason W.,Viet, Andrew Q.,Wang, Gren Z.,Sehon, Clark A.,Behm, David J.,Wu, Zining,Carballo, Luz H.,Douglas, Stephen A.,Neeb, Michael J.
scheme or table, p. 4470 - 4473 (2009/04/06)
Aminomethylpiperazines, reported previously as being κ-opioid receptor agonists, were identified as lead compounds in the development of selective urotensin receptor antagonists. Optimized substitution of the piperazine moiety has provided high affinity u
