23095-31-0

Basic information

• Product Name: 3,4-DIMETHOXYBENZENESULFONYL CHLORIDE
• Synonyms: TIMTEC-BB SBB003242;ASISCHEM D48920;ART-CHEM-BB B019393;3,4-DIMETHOXYBENZENESULFONYL CHLORIDE;3,4-DIMETHOXYBENZENESULPHONYL CHLORIDE;AKOS BBS-00006964;AKOS B019393;3,4-DIMETHOXYBENZENESULFONYL CHLORIDE,98 %
• CAS NO: 23095-31-0
• Molecular Formula: C₈H₉ClO₄S
• Molecular Weight: 236.67
• Product Categories: Benzenesulfonyl chloride;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds;Building Blocks;Chemical Synthesis;Organic Building Blocks;Sulfonyl Halides;Sulfur Compounds
• Mol File: 23095-31-0.mol
• Article Data: 6

Chemical Properties

• Melting Point: 67-70 °C(lit.)
• Boiling Point: 346.2 °C at 760 mmHg
• Flash Point: 163.2 °C
• Appearance: Off-white to beige/Crystalline Powder
• Density: 1.359 g/cm³
• Vapor Pressure: 0.000117mmHg at 25°C
• Refractive Index: 1.522
• Storage Temp.: 2-8°C
• Sensitive: Moisture Sensitive
• BRN: 2840170
• CAS DataBase Reference: 3,4-DIMETHOXYBENZENESULFONYL CHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIMETHOXYBENZENESULFONYL CHLORIDE(23095-31-0)
• EPA Substance Registry System: 3,4-DIMETHOXYBENZENESULFONYL CHLORIDE(23095-31-0)

Safety Data

• Hazard Codes: C,Xi
• Statements: 34
• Safety Statements: 26-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: II
• Hazardous Substances Data: 23095-31-0(Hazardous Substances Data)

Usage

Chemical Properties

off-white to beige crystalline powder

InChI:InChI=1/C8H9ClO4S/c1-12-7-4-3-6(14(9,10)11)5-8(7)13-2/h3-5H,1-2H3

Upstream product

• 700-96-9 3,4-dimethoxythiophenol 
• 91-16-7 1,2-dimethoxybenzene 

Downstream Products

• 93129-45-4 2-(3,4-Dimethoxy-benzenesulfonylamino)-4-methyl-pentanoic acid ethyl ester 
• 342372-36-5 PX117794 
• 2570-43-6 (3,4-dimethoxyphenyl)(methyl)sulfane 
• 93129-40-9 ethyl (3,4-dimethoxybenzenesulfonylamido)acetate 
• 142424-06-4 11-[2-(3,4-Dimethoxy-benzenesulfonylamino)-ethylsulfanyl]-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid methyl ester 
• 134479-40-6 C₃₄H₃₄N₈O₁₀S₅ 
• 128992-09-6 3,4-Dimethoxy-benzenesulfonic acid 1,5-bis-(4-chloro-phenyl)-1H-[1,2,4]triazol-3-yl ester 
• 93129-44-3 2-(3,4-Dimethoxy-benzenesulfonylamino)-3-phenyl-propionic acid methyl ester 
• 93129-43-2 3-(3,4-Dimethoxy-benzenesulfonylamino)-propionic acid ethyl ester 
• 93129-42-1 [(3,4-Dimethoxy-benzenesulfonyl)-methyl-amino]-acetic acid ethyl ester 
• 124869-81-4 3,4-Dimethoxy-N-[1-methyl-pyrrolidin-(2E)-ylidene]-benzenesulfonamide 
• 16939-35-8 3,4-Dimethoxy-benzolsulfon-N-(3,4-dichlor-phenyl)-amid 
• 41079-73-6 2,3,7,8-tetramethoxythianthrene 
• 18092-55-2 4,5-dimethoxy-2-nitrobenzenesulfonyl chloride 

Relevant articles and documents

Three-Component, Interrupted Radical Heck/Allylic Substitution Cascade Involving Unactivated Alkyl Bromides

Developing efficient and selective strategies to approach complex architectures containing (multi)stereogenic centers has been a long-standing synthetic challenge in both academia and industry. Catalytic cascade reactions represent a powerful means of rapidly leveraging molecular complexity from simple feedstocks. Unfortunately, carrying out cascade Heck-type reactions involving unactivated (tertiary) alkyl halides remains an unmet challenge owing to unavoidable β-hydride elimination. Herein, we show that a modular, practical, and general palladium-catalyzed, radical three-component coupling can indeed overcome the aforementioned limitations through an interrupted Heck/allylic substitution sequence mediated by visible light. Selective 1,4-difunctionalization of unactivated 1,3-dienes, such as butadiene, has been achieved by employing different commercially available nitrogen-, oxygen-, sulfur-, or carbon-based nucleophiles and unactivated alkyl bromides (>130 examples, mostly >95:5 E/Z, >20:1 rr). Sequential C(sp3)-C(sp3) and C-X (N, O, S) bonds have been constructed efficiently with a broad scope and high functional group tolerance. The flexibility and versatility of the strategy have been illustrated in a gram-scale reaction and streamlined syntheses of complex ether, sulfone, and tertiary amine products, some of which would be difficult to access via currently established methods.

Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists

The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.

Sulfonamide inhibitors of aspartyl protease

The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical