23095-31-0

Usage

Chemical Properties

off-white to beige crystalline powder

InChI:InChI=1/C8H9ClO4S/c1-12-7-4-3-6(14(9,10)11)5-8(7)13-2/h3-5H,1-2H3

Upstream product

• 91-16-7 1,2-dimethoxybenzene 
• 700-96-9 3,4-dimethoxythiophenol 

Downstream Products

• 63624-27-1 3,4-dimethoxybenzenesulfonamide 
• 18092-55-2 4,5-dimethoxy-2-nitrobenzenesulfonyl chloride 
• 41079-73-6 2,3,7,8-tetramethoxythianthrene 
• 124869-81-4 3,4-Dimethoxy-N-[1-methyl-pyrrolidin-(2E)-ylidene]-benzenesulfonamide 
• 93129-42-1 [(3,4-Dimethoxy-benzenesulfonyl)-methyl-amino]-acetic acid ethyl ester 
• 93129-43-2 3-(3,4-Dimethoxy-benzenesulfonylamino)-propionic acid ethyl ester 
• 93129-44-3 2-(3,4-Dimethoxy-benzenesulfonylamino)-3-phenyl-propionic acid methyl ester 
• 128992-09-6 3,4-Dimethoxy-benzenesulfonic acid 1,5-bis-(4-chloro-phenyl)-1H-[1,2,4]triazol-3-yl ester 
• 134479-40-6 C₃₄H₃₄N₈O₁₀S₅ 
• 142424-06-4 11-[2-(3,4-Dimethoxy-benzenesulfonylamino)-ethylsulfanyl]-6,11-dihydro-dibenzo[b,e]oxepine-2-carboxylic acid methyl ester 
• 93129-40-9 ethyl (3,4-dimethoxybenzenesulfonylamido)acetate 
• 23095-32-1 <(3,4-dimethoxyphenyl)sulfonyl>hydrazide 
• 2570-43-6 (3,4-dimethoxyphenyl)(methyl)sulfane 
• 199666-03-0 3,4-dimethoxy-N-[4-(3-nitrophenyl)-2-thiazolyl]benzenesulfonamide 

Relevant academic research and scientific papers

Three-Component, Interrupted Radical Heck/Allylic Substitution Cascade Involving Unactivated Alkyl Bromides

Developing efficient and selective strategies to approach complex architectures containing (multi)stereogenic centers has been a long-standing synthetic challenge in both academia and industry. Catalytic cascade reactions represent a powerful means of rapidly leveraging molecular complexity from simple feedstocks. Unfortunately, carrying out cascade Heck-type reactions involving unactivated (tertiary) alkyl halides remains an unmet challenge owing to unavoidable β-hydride elimination. Herein, we show that a modular, practical, and general palladium-catalyzed, radical three-component coupling can indeed overcome the aforementioned limitations through an interrupted Heck/allylic substitution sequence mediated by visible light. Selective 1,4-difunctionalization of unactivated 1,3-dienes, such as butadiene, has been achieved by employing different commercially available nitrogen-, oxygen-, sulfur-, or carbon-based nucleophiles and unactivated alkyl bromides (>130 examples, mostly >95:5 E/Z, >20:1 rr). Sequential C(sp3)-C(sp3) and C-X (N, O, S) bonds have been constructed efficiently with a broad scope and high functional group tolerance. The flexibility and versatility of the strategy have been illustrated in a gram-scale reaction and streamlined syntheses of complex ether, sulfone, and tertiary amine products, some of which would be difficult to access via currently established methods.

Oxyhalogenation of thiols and disulfides into sulfonyl chlorides/bromides using oxone-KX (X = Cl or Br) in water

A simple and rapid method for efficient synthesis of sulfonyl chlorides/bromides by oxyhalogenation of thiols and disulfides with oxone-KX (X = Cl or Br) using water as the solvent is described. This journal is the Partner Organisations 2014.

Phenylenediamine urotensin-II receptor antagonists and CCR-9 antagonists

The present invention relates to urotensin II receptor antagonists, CCR-9 antagonists, pharmaceutical compositions containing them and their use.

New compounds

The present invention relates to substituted bis-arylsulfonamide and arylsulfonamide compounds of the general formula (I) or the formula (II), which compounds are potentially useful for the prophylaxis and treatment of medical conditions relating to obesity, type II diabetes and/or disorders of the central nervous system.

Sulfonamide inhibitors of aspartyl protease

The present invention relates to a novel class of sulfonamides which are aspartyl protease inhibitors. In one embodiment, this invention relates to a novel class of HIV aspartyl protease inhibitors characterized by specific structural and physicochemical

Monomethylthio analogues of 1-(2,4,5-trimethoxyphenyl)-2-aminopropane

Regiospecific syntheses of the three monomethylthio analogues of 1-(2,4,5- trimethoxyphenyl)-2-aminopropane are described. The three isomeric amines were evaluated for potential psychotomimetic potency using the rabbit hyperthermia assay. Enantiomeric com