1053231-38-1

Basic information

• Product Name: (2R,6R)-2,6-dimethyldihydro-2H-pyran-4(3H)-one
• Synonyms: (2R,6R)-2,6-dimethyldihydro-2H-pyran-4(3H)-one
• CAS NO: 1053231-38-1
• Molecular Weight: 128.171
• Mol File: 1053231-38-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (2R,6R)-2,6-dimethyldihydro-2H-pyran-4(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,6R)-2,6-dimethyldihydro-2H-pyran-4(3H)-one(1053231-38-1)
• EPA Substance Registry System: (2R,6R)-2,6-dimethyldihydro-2H-pyran-4(3H)-one(1053231-38-1)

Safety Data

• Hazardous Substances Data: 1053231-38-1(Hazardous Substances Data)

Upstream product

• 869293-25-4 (R)-5-((tert-butyldimethylsilyl)oxy)hex-1-en-3-one 
• 190912-17-5 (R)-2-methyl-2,3-dihydro-4H-pyran-4-one 
• 676-58-4 methylmagnesium chloride 
• 1393537-60-4 (E)-5-((R)-tert-butyldimethylsilyloxy)-1-(piperidin-1-ylimino)hexan-3-one 
• 917-54-4 methyllithium 
• 19185-89-8 2-methyl-2,3-dihydro-4H-pyran-4-one 

Downstream Products

• 1393645-23-2 dimethyl (4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl((2S,5S)-5-methyl-2,1-pyrrolidinediyl)((1S)-1-((2R,6R)-2,6-dimethyltetrahydro-2H-pyran-4-yl)-2-oxo-2,1-ethanediyl)))biscarbamate 
• 1393537-51-3 dimethyl ((3-methyl-4,4'-biphenyldiyl)bis(1H-imidazole-4,2-diyl((2S,5S)-5-methyl-2,1-pyrrolidinediyl)((1S)-1-((2R,6R)-2,6-dimethyltetrahydro-2H-pyran-4-yl)-2-oxo-2,1-ethanediyl)))biscarbamate 
• 1393537-53-5 dimethyl ((3-fluoro-4,4'-biphenyldiyl)bis(1H-imidazole-4,2-diyl((2S,5S)-5-methyl-2,1-pyrrolidinediyl)((1S)-1-((2R,6R)-2,6-dimethyltetrahydro-2H-pyran-4-yl)-2-oxo-2,1-ethanediyl)))biscarbamate 
• 1393537-57-9 dimethyl (4,4'-biphenyldiylbis(1H-imidazole-4,2-diyl((2S)-2,1-pyrrolidinediyl)((1S)-1-((2R,6R)-2,6-dimethyltetrahydro-2H-pyran-4-yl)-2-oxo-2,1-ethanediyl)))biscarbamate 
• 1620545-73-4 C₁₈H₂₃NO₅ 

Relevant articles and documents

A Scalable Synthesis of (R,R)-2,6-Dimethyldihydro-2H-pyran-4(3H)-one

A scalable synthesis of (R,R)-2,6-dimethyldihydro-2H-pyran-4(3H)-one is reported. Key to this strategy is the Ti(OiPr)4-catalyzed Kulinkovich cyclopropanation of silyl protected (R)-ethyl 3-hydroxybutanoate, and subsequent oxidative fragmentati

INHIBITORS OF SERINE PROTEASES

The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt or mixtures thereof that inhibit serine protease activity, particularly the activity of hepatitis C virus NS3-NS4A protease.