1053253-08-9

Upstream product

• 184717-28-0 (S)-2-(4-tert-butyl-2-oxo-1,3-oxazolidin-3-yl)acetyl chloride 
• 184717-19-9 (S)-2-(4-tert-butyl-2-oxo-1,3-oxazolidin-3-yl)acetic acid 
• 54705-42-9 (S)-4-tert-butyloxazolidin-2-one 
• 184717-21-3 (S)-3-{(2S,3S)-1-Benzyl-2-[(S)-1-(tert-butyl-dimethyl-silanyloxy)-ethyl]-4-oxo-azetidin-3-yl}-4-tert-butyl-oxazolidin-2-one 

Downstream Products

• 184716-95-8 (S)-3-((2S,3S)-2-Acetyl-1-benzyl-4-oxo-azetidin-3-yl)-4-phenyl-oxazolidin-2-one 
• 1027933-53-4 (S)-3-((2S,3S)-2-Acetyl-1-benzyl-4-oxo-azetidin-3-yl)-4-tert-butyl-oxazolidin-2-one 

Relevant academic research and scientific papers

A study on the asymmetric synthesis of β-lactams through double stereodifferentiating cycloaddition reactions

The cycloaddition reaction of chiral aminoketenes, generated from their corresponding acid chlorides and triethylamine, with chiral imines is evaluated as the most direct approach for the construction of cis-β-lactams with the absolute stereochemistry at the C3 and C4 positions being controlled by the ketene partner, independently of the absolute stereochemistry of the imine component.