105326-95-2

Basic information

• Product Name: Benzenamine, 4-(2-quinolinylmethoxy)-
• CAS NO: 105326-95-2
• Molecular Formula: C16H14N2O
• Molecular Weight: 250.3
• Mol File: 105326-95-2.mol
• Article Data: 13

Chemical Properties

• CAS DataBase Reference: Benzenamine, 4-(2-quinolinylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine, 4-(2-quinolinylmethoxy)-(105326-95-2)
• EPA Substance Registry System: Benzenamine, 4-(2-quinolinylmethoxy)-(105326-95-2)

Safety Data

• Hazardous Substances Data: 105326-95-2(Hazardous Substances Data)

Upstream product

• 105326-63-4 N-acetyl-4-(2-quinolinylmethyloxy)phenylamine 
• 100-02-7 4-nitro-phenol 
• 4377-41-7 2-Chloromethylquinoline 
• 107813-50-3 2-(4-nitro-phenoxymethyl)-quinoline 

Downstream Products

• 102649-89-8 N-[4-(Quinolin-2-ylmethoxy)-phenyl]-succinamic acid methyl ester 
• 136694-19-4 4-(quinolin-2-ylmethoxy)-phenylhydrazine 
• 135334-38-2 (S,R)-2-[4-(2-Quinolylmethyloxy)-anilino]-2-phenyl acetic acid ethyl ester 
• 132395-13-2 2-(4-n-Pentylaminophenoxymethyl)quinoline 
• 135805-98-0 N-(4-Mesylphenyl)-N'-4-(quinolin-2-yl-methoxy)phenyl-thiourea 
• 1344653-81-1 1-benzyl-3-(5-tertbutyl-1,3,4-thiadiazol-2-yl)-1-[4-(quinoline-2-ylmethoxy)phenyl]urea 
• 1344653-87-7 4,4,4-trifluoro-N-pyridin-3-ylmethyl-N-[4-(quinolin-2-ylmethoxy)-phenyl]-butyramide 
• 898563-81-0 [4-(quinolin-2-ylmethoxy)-phenyl]-hydrazine hydrochloride 
• 119481-29-7 C,C,C-Trifluoro-N-[4-(quinolin-2-ylmethoxy)-phenyl]-methanesulfonamide 

Relevant articles and documents

HETEROARYL COMPOUNDS AS PDE10A INHIBITORS

The present invention provides heteroaryl compounds as Phosphodiesterase 10A (PDE I OA) inhibitors. In particular, compounds described herein are useful for treating or preventing diseases, conditions and/or disorders by inhibiting Phosphodiesterase 10A enzyme. Also provided herein are processes for preparing compounds described herein, Formula (I), intermediates used in their synthesis, pharmaceutical compositions thereof.

(Quinolin-2-ylmethoxy)indoles as inhibitors of the biosynthesis of leukotrienes

Compounds having the formula I: STR1 are inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating diarrhea, hypertension, angina, platelet aggregation, cerebral spasm, premature labor, spontaneous abortion, dysmenorrhea, and migraine.

Amorphous (quinolin-2-ylmethoxy)indole compounds which have useful pharmaceutical utility

A form of 3-[N-(p-chlorobenzyl)-3-(t-butylthio)-5-(quinolin-2-ylmethoxy)indol-2-yl]-2,2-dimethylpropanoic acid sodium salt, obtained by freeze or spray drying, is more soluble in water than the crystalline form thereof. The compound is useful as an anti-a