1053265-01-2

Upstream product

• 67-56-1 methanol 
• 201230-82-2 carbon monoxide 
• 21535-74-0 (4aS,R)-8-methoxy-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline 
• 478407-26-0 2-{[(6-Methoxy-2-quinolyl)methyl]amino}ethanol 
• 478407-27-1 2-{[(6-Methoxy-1,2,3,4-tetrahydro-2-quinolyl)methyl]amino}ethanol 
• 89060-22-0 6-methoxyquinoline-2-carboxaldehyde 
• 1078-28-0 6-methoxyquinaldine 
• 21535-78-4 3-benzyl-8-methoxy-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline 

Downstream Products

• 1053266-42-4 Methyl 3-(2-phenoxybenzyl)-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline-8-carboxylate 
• 1053265-03-4 methyl (4aS,R)-3-[(4'-chloro-[1,1'-biphenyl]-2-yl)methyl]-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline-8-carboxylate 
• 1053265-04-5 (4aS,R)-3-[(4'-chloro-[1,1'-biphenyl]-2-yl)methyl]-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinoline-8-carboxylic acid hydrochloride 
• 1044900-36-8 N-({(4aS,R)-3-[(4'-chloro-[1,1'-biphenyl]-2-yl)methyl]-2,3,4,4a,5,6-hexahydro-1H-pyrazino[1,2-a]quinolin-8-yl}carbonyl)-4-({(1R)-3-(dimethylamino)-1-[(phenyl-sulphanyl)methyl]propyl}amino)-3-nitrobenzenesulphonamide 

Relevant academic research and scientific papers

Tricyclic compounds, a process for their preparation and pharmaceutical compositions containing them

Compounds of formula (I): wherein A represents a 5, 6 or 7-membered (hetero)aromatic or non-aromatic ring,n and n′ represent 0, 1 or 2X represents an alkylene chain as defined in the description,R3 represents an aryl or heteroaryl group,one of the groups R1 and R2 represents a hydrogen atom and the other represents a group of formula (II) as defined in the description. Medicinal products containing the same which are useful in treating conditions involving a defect in apoptosis.