105330-01-6Relevant academic research and scientific papers
Copper-Catalyzed Fluoroolefination of Silyl Enol Ethers and Ketones toward the Synthesis of β-Fluoroenones
Li, Yanlin,Liu, Jing,Zhao, Shuang,Du, Xuzhao,Guo, Minjie,Zhao, Wentao,Tang, Xiangyang,Wang, Guangwei
, p. 917 - 920 (2018/02/22)
A general and facile synthetic method for β-fluoroenones from silyl enol ethers or ketones, with a copper-amine catalyst system, has been developed. The reaction proceeded by a tandem process of difluoroalkylation-hydrolysis-dehydrofluorination. This method is characterized by high yields, excellent Z/E ratios, a low-cost catalyst, and a broad substrate scope. The synthetic potential of β-fluoroenones has been demonstrated by the construction of various complicated organofluorine molecules.
Tetrabutylammonium and polymer-supported dihydrogentrifluoride: new reagents for the hydrofluorination of activated acetylenic bonds
Cousseau, Jack,Albert, Patrice
, p. 910 - 915 (2007/10/02)
Tetrabutylammonium and polymer-supported dihydrogentrifluoride are easily prepared by a phase-transfer procedure from the corresponding fluoride salts.These stable new dihydrogentrifluoride salts allow the addition of HF under mild conditions to carbon-ca
