105337-73-3

Upstream product

• 5631-95-8 2,3-dichlorotetrahydro-2H-pyran 
• 95-46-5 2-methylphenyl bromide 
• 110-87-2 3,4-dihydro-2H-pyran 
• 195062-59-0 2-methylphenylboronic acid pinacol ester 
• 87436-78-0 (4-hydroxybutyl)-triphenylphosphonium bromide 
• 529-20-4 2-methylphenyl aldehyde 
• 939400-91-6 5-o-tolylpent-4-enoic acid ethyl ester 
• 445477-03-2 5-(2-methylphenyl)-4-pentenoic acid 

Downstream Products

• 1380523-52-3 (E)-5-o-tolylpent-4-enyl methanesulfonate 
• 1380523-12-5 (E)-dimethyl 2-(5-o-tolylpent-4-enyl)malonate 
• 1426692-66-1 3-chloro-2-o-tolyltetrahydro-2H-pyran 
• 15382-80-6 1-o-Tolyl-5-<4-amino-2-methoxy-phenoxy>-pentan 
• 109808-88-0 1-o-Tolyl-5-(4-nitro-2-methoxy-phenoxy)-pentan 
• 105474-56-4 O-(5-bromopentyl)-toluene 
• 107055-19-6 5-o-Tolyl-pentanol-⁽¹⁾ 

Relevant academic research and scientific papers

Nickel-catalyzed ring-opening cross-coupling of cyclic alkenyl ethers with arylboronic esters via carbon-oxygen bond cleavage

We have developed a nickel-catalyzed cross-coupling reaction of cyclic alkenyl ethers with arylboronic esters that leads to the formation of unsaturated alcohols via ring-opening by the cleavage of a C(sp2)-O bond. The use of 1,3-dicyclohexylimidazol-2-ylidene as the ligand is essential to promote this cross-coupling process.

Asymmetric 5-endo chloroetherification of homoallylic alcohols toward the synthesis of chiral β-chlorotetrahydrofurans

An asymmetric 5-endo chloroetherification of homoallylic alcohols is successfully developed that employs an easily available quaternary ammonium salt derived from cinchonine as a conventional organocatalyst. This approach provides ready access to β-chloro

Manganese(III) acetate mediated oxidative radical cyclizations. Toward vicinal all-carbon quaternary stereocenters

Manganese(III) acetate mediated oxidative radical cyclizations have been used to synthesize a range of densely functionalized and sterically congested cyclopentane-lactones. A number of the resulting lactones contain vicinal all-carbon quaternary stereocenters adjacent to a tertiary benzylic stereocenter and are formed with high levels of stereocontrol.

A highly enantioselective approach towards 2-substituted 3-bromopyrrolidines

A facile and highly enantioselective approach towards 2-substituted 3-bromopyrrolidines has been developed. The process involves an amino-thiocarbamate catalyzed bromoaminocyclization of 1,2-disubstituted olefinic amides. The pyrrolidine products could re