105474-56-4

Upstream product

• 111-24-0 1,5-dibromo-pentane 
• 529-19-1 2-Methylbenzonitrile 
• 95-46-5 2-methylphenyl bromide 
• 105337-73-3 (E)-5-o-tolylpent-4-en-1-ol 
• 5631-95-8 2,3-dichlorotetrahydro-2H-pyran 
• 107055-19-6 5-o-Tolyl-pentanol-⁽¹⁾ 

Downstream Products

• 109808-88-0 1-o-Tolyl-5-(4-nitro-2-methoxy-phenoxy)-pentan 
• 15382-80-6 1-o-Tolyl-5-<4-amino-2-methoxy-phenoxy>-pentan 

Relevant academic research and scientific papers

Reductive activation of arenes 21. Reaction of products of two-electron reduction of arenecarbonitriles by alkali metals in liquid ammonia with bromo-and dibromoalkanes

Reductive alkylation of benzonitrile, ortho-, meta-, para-tolunitriles, and 1-naphthonitrile by sequential action of alkali metal and alkyl bromide in liquid ammonia results in corresponding alkylarenes and 1-alkyl-1- cyanocyclohexa-2,5-dienes. The experimental conditions for target synthesis of the specified products are found. A method of synthesis of 1-(ω- bromoalkyl)-1-cyanocyclohexa-2,5-dienes based on the interaction of two-electronic reduction products of aromatic nitriles with α,ω- dibromoalkanes Br(CH2)nBr (n = 3-5) is developed.