1053628-43-5Relevant articles and documents
A flexible common approach to α-substituted serines and alanines: Diastereoconvergent syntheses of sphingofungins E and F
Wang, Bing,Lin, Guo-Qiang
scheme or table, p. 5038 - 5046 (2010/02/28)
A flexible common approach for the asymmetric syntheses of sphingofungins E and F is reported, with efficient use of both diastereomers of the Baylis-Hillman adduct in a stereoconvergent manner. Pronounced steric effects of the 2-substituents in diastereo
The first total synthesis of sphingofungin E and the determination of its stereochemistry
Wang,Yu,Lin
, p. 904 - 906 (2007/10/03)
The total synthesis of sphingofungin E has been realized for the first time and its absolute configurations were established. Starting from L-(+)-tartaric acid, our synthesis featured substrate-controlled asymmetric dihydroxylation, regiospecific epoxide formation and Hatakeyama reaction to construct the contiguous chiral centers in the target molecule.