1053656-57-7

Basic information

• Product Name: 4-chloro-5,8-dihydro-6H-pyrido[3,4-d]pyriMidine-7-carboxylic acid tert-butyl ester
• Synonyms: 4-chloro-5,8-dihydro-6H-pyrido[3,4-d]pyriMidine-7-carboxylic acid tert-butyl ester;tert-Butyl 4-chloro-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H);tert-butyl 4-chloro-6,8-dihydro-5H-pyrido[3,4-d]pyrimidine-7-carboxylate
• CAS NO: 1053656-57-7
• Molecular Formula: C₁₂H₁₆ClN₃O₂
• Molecular Weight: 269.72734
• EINECS: -0
• Mol File: 1053656-57-7.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 395.8±42.0 °C(Predicted)
• Appearance: /
• Density: 1.266±0.06 g/cm3(Predicted)
• PKA: -0.04±0.20(Predicted)
• CAS DataBase Reference: 4-chloro-5,8-dihydro-6H-pyrido[3,4-d]pyriMidine-7-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-5,8-dihydro-6H-pyrido[3,4-d]pyriMidine-7-carboxylic acid tert-butyl ester(1053656-57-7)
• EPA Substance Registry System: 4-chloro-5,8-dihydro-6H-pyrido[3,4-d]pyriMidine-7-carboxylic acid tert-butyl ester(1053656-57-7)

Safety Data

• Hazardous Substances Data: 1053656-57-7(Hazardous Substances Data)

Usage

General Description

4-chloro-5,8-dihydro-6H-pyrido[3,4-d]pyrimidine-7-carboxylic acid tert-butyl ester is a chemical compound that is commonly used in pharmaceutical research and drug development. It is a tert-butyl ester derivative of the pyrido[3,4-d]pyrimidine carboxylic acid, and its structure includes a chlorine atom in the 4-position. 4-chloro-5,8-dihydro-6H-pyrido[3,4-d]pyriMidine-7-carboxylic acid tert-butyl ester has been studied for its potential pharmacological activity, particularly as an inhibitor of certain enzymes and receptors in the body. It is also utilized as a building block for the synthesis of other organic compounds with potential therapeutic applications. Additionally, its unique structure and properties make it a valuable tool for medicinal chemists and researchers in the development of new drugs.

Upstream product

• 63876-32-4 4-[benzyl(ethoxycarbonylmethyl)amino]butyric acid ethyl ester 
• 62458-96-2 7-benzyl-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4(3H)-one 
• 70637-75-1 ethyl 3-oxopiperidine-4-carboxylate 
• 1142188-60-0 4-hydroxy-5,8-dihydro-6H-pyrido[3,4-d]pyrimidine-7-carboxylic acid tert-butyl ester 
• 39514-19-7 ethyl 1-benzyl-3-oxo-4-piperidinecarboxylate 
• 71233-25-5 ethyl 1-tert-butoxycarbonyl-3-oxopiperidine-4-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1142188-60-0 4-oxo-4,5,6,8-tetrahydro-3H-pyrido[3,4-d]pyrimidine-7-carboxylic acid tert-butyl ester 

Downstream Products

• 1274802-46-8 N-{7-[2-(4-chlorobiphenyl)-5,5-dimethylcyclohex-1-enylmethyl]-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl}-4-((R)-3-morpholin-4-yl-1-phenylsulfanylmethyl-propylamino)-3-trifluoromethanesulfonylbenzenesulfonamide 
• 1274803-40-5 N-(7-(1-((4'-chlorobiphenyl-2-yl)methyl)-3-fluoropiperidin-4-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-4-((R)-4-morpholino-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)benzenesulfonamide 
• 1274804-70-4 (R)-4-(4-morpholino-1-(phenylthio)butan-2-ylamino)-N-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-3-(trifluoromethylsulfonyl)-benzenesulfonamide 
• 1421687-46-8 tert-butyl 4-methoxy-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate 
• 1274804-57-7 (R)-tert-butyl 4-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-(trifluoromethylsulfonyl)phenylsulfonamido)-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate 
• 1421687-50-4 4-{4-[4-((R)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-3-trifluoromethanesulfonyl-benzenesulfonylamino]-8-oxo-5,8-dihydro-6H-pyrido[3,4-d]pyrimidin-7-yl}-piperidine-1-carboxylic acid tert-butyl ester 
• 1274802-50-4 (R)-N-(7-(1-((4'-chloro-biphenyl-2-yl)methyl)piperidin-4-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)-4-((4-(dimethylamino)-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)benzenesulfonamide 
• 1274804-71-5 4-((R)-3-dimethylamino-1-phenylsulfanylmethyl-propylamino)-N-(5,6,7,8-tetrahydro-pyrido[3,4-d]pyrimidin-4-yl)-3-(trifluoromethanesulfonyl)benzenesulfonamide 
• 1196157-06-8 4-chloro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine 

Relevant articles and documents

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