105370-60-3

Basic information

• Product Name: Benzenemethanamine, a-butyl-, (S)-
• CAS NO: 105370-60-3
• Molecular Formula: C11H17N
• Molecular Weight: 163.263
• Mol File: 105370-60-3.mol
• Article Data: 16

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, a-butyl-, (S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, a-butyl-, (S)-(105370-60-3)
• EPA Substance Registry System: Benzenemethanamine, a-butyl-, (S)-(105370-60-3)

Safety Data

• Hazardous Substances Data: 105370-60-3(Hazardous Substances Data)

Upstream product

• 862776-58-7 (S)-N-benzylidene-2-methylpropane-2-sulfinamide 
• 932-90-1 Benzaldoxime 
• 1313531-70-2 (1S,1'S)-N-(1',3'-diphenylpropan-1'-oxy)-1-phenylpentan-1-amine 
• 100-47-0 benzonitrile 
• 100-52-7 benzaldehyde 
• 131154-12-6 4-Methyl-benzenesulfinic acid [1-phenyl-pent-(E)-ylidene]-amide 
• 249920-08-9 2,4-diphenyl-1,3-oxazolidine 
• 155234-14-3 (1S,2R,3S,4R)-3-(2,2-Dimethyl-propoxy)-4,7,7-trimethyl-bicyclo[2.2.1]heptane-2-sulfinic acid 1-phenyl-meth-(E)-ylideneamide 
• 155234-11-0 C₂₂H₃₃NOS 
• 260998-33-2 (E)-(S)-(-)-O-(1-phenylbutyl) benzaldehyde oxime 
• 185758-21-8 (S)-(-)-N-(1-phenylbutoxy)phthalimide 
• 757195-17-8 benzaldehyde O-[(2R)-2-hydroxy-2-phenylethyl]oxime 
• 321-97-1 (1R,2R)-pseudoephedrine 
• 63160-16-7 4-nitro-N-[(1E)-phenylmethylidene]benzene-1-sulfonamide 

Relevant articles and documents

Addition of Highly Polarized Organometallic Compounds to N-tert-Butanesulfinyl Imines in Deep Eutectic Solvents under Air: Preparation of Chiral Amines of Pharmaceutical Interest

Highly polarized organometallic compounds of s-block elements are added smoothly to chiral N-tert-butanesulfinyl imines in the biodegradable d-sorbitol/choline chloride eutectic mixture, thereby granting access to enantioenriched primary amines after quantitatively removing the sulfinyl group. The practicality of the method is further highlighted by proceeding at ambient temperature and under air, with very short reaction times (2 min), enabling the preparation of diastereoisomeric sulfinamides in very good yields (74–98 %) and with a broad substrate scope, and the possibility of scaling up the process. The method is demonstrated in the asymmetric syntheses of both the chiral amine side-chain of (R,R)-Formoterol (96 % ee) and the pharmaceutically relevant (R)-Cinacalcet (98 % ee).

Catalytic asymmetric synthesis of β-sultams as precursors for taurine derivatives

β-Sultams, biologically interesting sulfonyl analogues of β-lactams, have been prepared by an organocata-lytic asymmetric formal [2+ 2]-cycloaddition approach of non-nucleophilic imines with alkyl sulfonyl chlorides. In the case of very electron poor N-to

β-Silylated homopropargylic amines via the asymmetric allenylboration of aldimines

(Chemical Equation Presented) The asymmetric synthesis of α-trimethylsilylpropargylic carbamines (7) through the addition of allenylboranes 4 to N-H aldimines is reported. The insertion of TMSCHN 2 into enantiomerically pure B-alkynyl-10-TMS-9-