1053794-42-5Relevant articles and documents
Efficient synthesis of N-protected amino/peptide Weinreb amides from T3P and DBU
Sharnabai,Nagendra,Vishwanatha,Sureshbabu, Vommina V.
, p. 478 - 482 (2013)
The reaction of Nα-protected amino/peptide acid with N,O-dimethylhydroxylamine hydrochloride in the presence of T3P and DBU to obtain enantiomerically pure Nα-protected amino/peptidyl Weinreb amides in high yields has been described. Fmoc-Ala-Weinreb amide 2a is obtained as single crystal, and its structure was determined through X-ray crystallography.