105401-73-8Relevant articles and documents
Lipase catalyzed esterification of cresols
Suresh Babu,Karanth,Divakar
, p. 1068 - 1071 (2007/10/03)
Esters of m- and p-cresols with organic acids having carbon chain lengths C2-C18 have been prepared by using lipases from porcine pancreas and Rhizomucor miehei. Gram level conversions are carried out under non-solvent conditions in case of shake flask experiments and continuous removal of water at bench-scale levels. Addition of 0.1 mL of 0.1M phosphate buffer at pH 7.0 to the reaction mixture shows better conversions. Optimization studies have been carried out for p-cresyl laurate synthesis using Rhizomucor miehei lipase which show a maximum conversion of 74.4 %. Better conversions are obtained with larger amounts of enzyme. Porcine pancreas lipase catalyzed synthesis of m- and p-cresyl esters show that under identical reaction conditions acids with lower carbon chain lengths (C2-C4) give ester yields above 30%, while those with longer carbon chain lengths give ester yields 30%.
Studies on Aromatic Sesquiterpenes. XI. Synthesis of 7-Isopropyl-3,5-dimethyl-1-naphthol
Tanaka, Juichi,Adachi, Kazuo
, p. 2102 - 2104 (2007/10/02)
Starting from m-cresol, the title new naphthol was synthesized through 4-methyl-3-(2-methoxy-4-methylbenzoyl)pentanoic acid as a key intermediate.